摘要
急性胰腺炎(acute pancreatitis,AP)是临床常见的急腹症之一,且发病率有逐渐上升的趋势。而AP的病程进展被证明与病人肠道菌群失衡密切相关。临床上也常运用抗生素、益生菌等疗法,以调节AP病人肠道菌群。更加深入与系统地了解肠道菌群失衡在AP进展中的作用及其相关机制,可能为未来AP的治疗带来新思路。
With a rising incidence,acute pancreatitis(AP)is one of the most common acute abdominal diseases.Its clinical progression has been closely correlated with gut microbiota dysbiosis.Antibiotics and probiotics are frequently applied for regulating intestinal flora of AP patients.A more in-depth and systematic understanding of the role of gut microbiota dysbiosis in the progression of AP and its related therapeutic mechanism may bring new concepts for managing AP in the future.
作者
赵传兵
张正乐
陶京
Zhao Chuanbing;Zhang Zhengle;Tao Jing(Department of General Surgery,Renmin Hospital,Wuhan University,Hubei Wuhan 430060,China)
出处
《腹部外科》
2022年第1期62-66,共5页
Journal of Abdominal Surgery
关键词
急性胰腺炎
肠道菌群
肠道菌群失衡
Acute pancreatitis
Gut microbiota
Gut microbiota dysbiosis