摘要
目的探讨百合固金汤联合生脉散加减方治疗肺结核患者的临床疗效。方法 100例肺结核患者,以随机数字表法分为常规组和实验组,各50例。常规组予以常规西药治疗,实验组在常规组基础上给予百合固金汤联合生脉散加减方治疗。比较两组临床疗效、临床症状缓解时间及免疫指标。结果实验组治疗总有效率98.0%高于常规组的84.0%,差异有统计学意义(P<0.05)。实验组乏力、消瘦、盗汗、低热缓解时间分别为(12.61±1.75)、(10.15±2.29)、(10.02±2.19)、(11.12±2.07)d,均短于常规组的(15.72±2.13)、(13.79±1.84)、(13.63±1.38)、(14.53±1.37)d,差异有统计学意义(P<0.05)。实验组CD3^(+)、CD4^(+)、CD8^(+)与CD4^(+)/CD8^(+)水平均优于常规组,差异有统计学意义(P<0.05)。结论相较于常规西药,以百合固金汤联合生脉散加减方治疗肺结核不仅能够提高其治疗效果,缓解患者临床症状的同时还能提高其免疫功能,用药安全性较高,适宜深入研究。
Objective To discuss the clinical efficacy of modified Baihe Gujin Decoction combined with Shengmai Powder in the treatment of pulmonary tuberculosis. Methods A total of 100 cases of pulmonary tuberculosis patients were divided into conventional group and experimental group by random numerical table,each with 50 cases. The conventional group was treated with conventional western medicine, and the experimental group was treated with modified Baihe Gujin Decoction combined with Shengmai Powder on the basis of the conventional group. The clinical efficacy, clinical symptom relief time and immune indicators were compared between the two groups. Results The total effective rate of treatment 98.0% in the experimental group was higher than 84.0% in the conventional group, and the difference was statistically significant(P<0.05). The relief time of fatigue, weight loss, night sweats, and low-grade fever in the experimental group were(12.61±1.75),(10.15±2.29),(10.02±2.19), and(11.12±2.07) d, which were shorter than(15.72±2.13),(13.79±1.84),(13.63±1.38),(14.53±1.37) d of the conventional group, and the difference was statistically significant(P<0.05). The levels of CD3^(+), CD4^(+), CD8^(+)and CD4^(+)/CD8^(+)in the experimental group were better than those in the conventional group, and the difference was statistically significant(P<0.05). Conclusion Compared with conventional western medicine,the combination of modified Baihe Gujin Decoction and Shengmai Powder can not only improve the therapeutic effect, relieve the clinical symptoms of patients, but also improve their immune function, which is safe and suitable for further study.
作者
靳秀春
JIN Xiu-chun(Dalian Tuberculosis Hospital,Dalian 116037,China)
出处
《中国现代药物应用》
2022年第1期212-214,共3页
Chinese Journal of Modern Drug Application
关键词
百合固金汤
生脉散加减方
肺结核
免疫指标
症状缓解时间
Baihe Gujin Decoction
Modified Shengmai Powder
Pulmonary tuberculosis
Immune indicators
Symptom relief time
