摘要
目的探讨定坤丹辅助治疗在腹腔镜术后卵巢子宫内膜异位症囊肿不孕患者中的应用效果。方法选取2019年3月到2020年3月于东莞广济医院接受腹腔镜手术治疗的84例卵巢子宫内膜异位囊肿不孕患者作为研究对象,采用简单随机化法将其分为对照组(42例)和观察组(42例)。对照组患者采用注射曲普瑞林治疗,观察组患者在曲普瑞林的基础上使用定坤丹辅助治疗。比较两组患者临床症状的严重程度量化评分,同时比较患者恢复排卵后卵泡生长速度、排卵日雌二醇水平及两组的并发症发生率、复发率及妊娠率。结果治疗后两组严重程度量化评分(包括主症和次症)低于本组治疗前,差异有统计学意义(P<0.05)。两组的妊娠率和复发率比较,差异无统计学意义(P>0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。观察组的卵泡生长速度观察组快于对照组,差异有统计学意义(P<0.05)。两组卵泡成熟时雌二醇值比较,差异无统计学意义(P>0.05)。结论定坤丹辅助治疗腹腔镜术后卵巢子宫内膜异位囊肿不孕患者可以有效减少疼痛和绝经症状,增加妊娠率同时降低患者复发率和并发症的发生率。
Objective To investigate the application effect of Dingkundan in the adjuvant treatment of infertility patients with ovarian endometriosis cyst after laparoscopic surgery.Methods From March 2018 to March 2020,84 infertile patients with ovarian endometriosis cyst treated by laparoscopic surgery in Dongguan Guangji Hospital were selected as the research objects,and they were divided into control group(42 cases)and observation group(42 cases)by simple randomization.The control group was treated with injection of Triptorelin,while the observation group was treated with Dingkundan on the basis of Triptorelin.The quantitative score of clinical symptom severity was compared between the two groups.At the same time,the follicular growth rate after ovulation,the level of estradiol on ovulation day,the incidence of complications,recurrence rate and pregnancy rate of the two groups were compared.Results After treatment,the quantitative severity scores(including primary and secondary symptoms)of the two groups were lower than before treatment,and the differences were statistically significant(P<0.05).There were no significant differences in pregnancy rate and recurrence rate between the two groups(P>0.05),and the incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The follicle growth rate of the observation group was faster than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in estradiol value at follicular maturation between the two groups(P>0.05).Conclusion Dingkundan adjuvant treatment of ovarian endometriosis cyst infertility patients after laparoscopic surgery can effectively reduce the pain and menopausal symptoms,increase the pregnancy rate,and reduce the recurrence rate and the incidence of complications.
作者
黎译励
何芝兰
LI Yili;HE Zhilan(Department of Reproduction,Dongguan Guangji Hospital,Guangdong Province,Dongguan523690,China)
出处
《中国当代医药》
CAS
2022年第3期13-16,共4页
China Modern Medicine
基金
广东省东莞市社会科技发展(一般)项目(202050715062627)。
