摘要
目的探讨不孕女性需求性激素六项水平变化及其指导意义。方法选取2019年1月至2020年7月我院91例不孕女性作为观察组,同期纳入53例已婚已育健康女性作为对照组。统计对照组和观察组不同月经情况下的血清卵泡刺激素(FSH)、睾酮(T)、孕酮(P)、促黄体生成素(LH)、雌二醇(E2)、泌乳素(PRL)。结果(1)观察组原发性不孕、继发性不孕患者血清FSH、P、E2水平低于对照组,LH、PRL水平高于对照组(P<0.05),原发性不孕患者血清E2水平低于继发性不孕患者,LH水平高于继发性不孕患者(P<0.05);(2)原发性不孕、继发性不孕月经紊乱和月经正常患者血清T、P、E2、FSH水平比较,无显著差异(P>0.05),原发性不孕、继发性不孕月经紊乱患者血清LH、PRL水平高于月经正常患者(P<0.05)。结论血清性激素LH、PRL、E2水平检测能较为全面反映不孕症类型或月经紊乱情况,对指导临床用药意义重大。
Objective To explore the six levels of sex hormones in infertile women and their guiding significance. Methods From January 2019 to July 2020, 91 infertile women in our hospital were selected as the observation group, and 53 married and child-bearing healthy women were included as the control group during the same period. The serum follicle stimulating hormone(FSH), testosterone(T), progesterone(P), luteinizing hormone(LH),estradiol(E2), and prolactin(PRL) of different menstrual conditions in the two groups and the observation group were counted. Results(1) The serum FSH, P, E2 levels of patients with primary infertility and secondary infertility in the observation group were lower than those of the control group, and the levels of LH and PRL were higher than those of the control group(P<0.05). The serum E2 level of patients with primary infertility was lower than that of patients with secondary infertility, and the level of LH was higher than that of patients with secondary infertility(P<0.05).(2)There was no significant difference in serum T, P, E2, FSH levels in patients with primary infertility, secondary infertility, menstrual disorders, and normal menstruation(P>0.05). The serum LH and PRL levels of patients with primary infertility and secondary infertility with menstrual disorders were higher than those of patients with normal menstruation(P<0.05). Conclusion The detection of serum levels of sex hormones LH, PRL, and E2 can more comprehensively reflect the type of infertility or menstrual disorders, and is of great significance in guiding clinical medication.
作者
李耀伟
LI Yao-wei(Department of Clinical Laboratory,the Third People's Hospital of Luohe(Luohe Maternal and Child Health Hospital),Luohe 462300,Henan Province,China)
出处
《罕少疾病杂志》
2022年第2期108-110,共3页
Journal of Rare and Uncommon Diseases
关键词
不孕
促黄体生成素
卵泡刺激素
泌乳素
孕酮
Infertility
Luteinizing Hormone
Follicle Stimulating Hormone
Prolactin
Progesterone
