摘要
研究血清肝素结合蛋白(HBP)、红细胞分布宽度(RDW)联合急性生理与慢性健康评分量表(APACHⅡ)在评估急性胰腺炎合并感染中的预测价值。研究发现,相比于未合并感染组患者,合并感染患者HBP、RDW、C反应蛋白、白细胞计数、降钙素原显著更高(P<0.05)、APACHEⅡ评分显著更高(P<0.05)。血清HBP、RDW以及APACHEⅡ评分都是急性胰腺炎患者合并感染的预测指标,三者联合检测能够有效提高灵敏度和特异度,预测价值较高。
The purpose of this study was to investigate the predictive value of serum heparin binding protein(HBP),red blood cell distribution width(RDW)combined with acute physiology and chronic health evaluationⅡ(APACH II)score in acute pancreatitis complicated with infection.Our findings showed that,compared with those without complicating infection,patients with acute pancreatitis complicated with infection had significantly higher levels of serum HBP,RDW,C-reactive protein,white blood cell count,and procalcitonin(P<0.05),as well as higher APACHE II scores(P<0.05).While any of serum HBP,RDW and APACHEⅡscore is predictive of complicating infection in patients with acute pancreatitis,combination use of the three can effectively improve the sensitivity and specificity of the prediction and therefore appears more valuable.
作者
李宇
杨春
张效良
Li Yu;Yang Chun;Zhang Xiaoliang(Department of Gastroenterology,Nanjing Tongren Hospital Affiliated to Southeast University School of Medicine,Nanjing,Jiangsu 211102,China)
出处
《中华生物医学工程杂志》
CAS
2021年第5期549-552,共4页
Chinese Journal of Biomedical Engineering
