摘要
目的分析重症急性胰腺炎(severe acute pancreatitis,SAP)在ICU中疗效。方法随机选取该院2016年1月—2019年8月收治确诊为100例SAP患者作为研究对象,开展随机分组,观察组(50例,ICU综合治疗)和对照组(50例,常规治疗),对比两组患者治疗有效率,治疗前后血淀粉酶(AMS)、白细胞介素-6(IL-6)、C-反应蛋白(CRP)水平,在腹痛减轻、肠道恢复正常、血液淀粉酶恢复正常、脱离呼吸机等方面的所用时间,在腹腔脓肿、呼吸衰竭、假性囊肿等方面并发症发生率,在随访一年时间内的生存率和病死率。结果治疗后,观察组患者治疗有效率、生存率均高于对照组,差异有统计学意义(χ^(2)=7.111、11.977,P<0.05),治疗后,观察组的AMS(110.14±4.01)IU/L、IL-6(140.04±5.36)pg/mL、CRP水平(119.32±50.36)IU/L优于对照组的(115.25±6.39)IU/L、(146.25±8.66)pg/mL、(170.52±80.36)IU/L,差异有统计学意义(t=4.789、4.312、3.818,P<0.05)。对两种治疗方案下SAP患者记录,观察组症状恢复时间短于对照组,病死率低于对照组,同时,在并发症的统计下,观察组更低,差异有统计学意义(P<0.05)。结论ICU综合治疗可提升SAP患者临床治疗有效率和生存率,改善血清水平,缩短症状恢复时间,减少并发症。
Objective To analyze the efficacy of severe acute pancreatitis(SAP)in ICU.Methods From January 2016 to August 2019,100 SAP patients were admitted to the hospital were randomly selected as the research objects.Caltied out random grouping,the observation group(50 cases,ICU comprehensive treatment)and the control group(50 cases,conventional treatment),compared the effective rate,blood amylase(AMS),interleukin-6(IL-6),C-reative protein(CRP)levels of treatment between the two groups of patients before and after treatment,reduce abdominal pain,return to normal intestines,return to normal blood amylase,and leave the ventilator,etc.In terms of time spent,the incidence of complications in abdominal abscess,respiratory failure,pseudocyst,etc.,the survival rate and mortality rate within one year of follow-up.Results After treatment,the effective rate and survival rate of patients in the observation group were higher than those in the control group,and the difference was statistically significant(χ^(2)=7.111,11.977,P<0.05).After treatment,the observation group’s AMS(110.14±4.01)IU/L,IL-6(140.04±5.36)pg/mL,CRP level(119.32±50.36)IU/L,better than the control group(115.25±6.39)IU/L,(146.25±8.66)pg/mL,(170.52±80.36)IU/L,the difference was statistically significant(t=4.789,4.312,3.818,P<0.05).Records of SAP patients under the two treatment options showed that the observation group had a shorter recovery time of symptoms than the control group,and the fatality rate was lower than that of the control group.At the same time,under the statistics of complications,the observation group was also lower,and the difference was statistically significant(P<0.05).Conclusion ICU comprehensive treatment can improve the clinical treatment efficiency and survival rate of SAP patients,improve serum levels,shorten symptom recovery time,and reduce complications.
作者
杨俊明
YANG Junming(Department of Critical Care Medicine,Yuxi People's Hospital,Yuxi,Yunnan Province,653100 China)
出处
《中外医疗》
2021年第32期35-38,共4页
China & Foreign Medical Treatment
关键词
重症急性胰腺炎
ICU综合治疗
应用效果
Severe acute pancreatitis
Comprehensive ICU treatment
Application effect
