摘要
目的研究冠心病介入治疗对不同年龄段患者心肌运动的影响。方法148例冠心病患者,均采用股动脉介入治疗,根据患者的年龄分为中年组(35~50岁,74例)与老年组(≥65岁,74例)。比较两组患者治疗前后的左室收缩功能指标、左室收缩同步性指标。结果中年组患者治疗前的左室舒张末期容积、左室收缩末期容积、左室射血分数分别为(96.24±15.49)ml、(45.61±8.24)ml、(55.26±6.24)%,治疗后分别为(99.31±12.54)ml、(39.15±8.47)ml、(57.82±6.86)%;老年组患者治疗前的左室舒张末期容积、左室收缩末期容积、左室射血分数分别为(95.42±15.43)ml、(47.61±3.06)ml、(46.27±9.42)%,治疗后分别为(99.64±10.26)ml、(46.24±3.25)ml、(50.26±9.84)%。两组患者治疗前后组内左室舒张末期容积以及治疗前组间左室收缩末期容积比较,差异均无统计学意义(P>0.05)。治疗后6个月,两组患者左室收缩末期容积均低于治疗前,且中年组低于老年组,差异均具有统计学意义(P<0.05);两组患者左室射血分数均高于治疗前,差异均具有统计学意义(P<0.05)。治疗后6个月,两组患者的Tmsv16-SD、Tmsv12-SD均较治疗前降低,差异有统计学意义(P<0.05)。结论介入治疗对中老年冠心病患者的心肌运动均有显著改善,其中对中年患者左室收缩功能的改善效果更大,值得在临床上推广。
Objective To study the effects of interventional therapy of coronary heart disease on myocardial motion in patients of different ages.Methods A total of 148 patients with coronary heart disease were treated with interventional therapy through femoral artery approaches.According to the age of the patients,they were divided into middle-aged group(35-50 years old,74 cases)and elderly group(≥65 years old,74 cases).The left ventricular systolic function indexes and left ventricular synchronism indexes before and after treatment were compared between the two groups.Results In the middle-aged group,the left ventricular end-diastolic volume,left ventricular end-systolic volume,and left ventricular ejection fraction before treatment were(96.24±15.49)ml,(45.61±8.24)ml,and(55.26±6.24)%,which were(99.31±12.54)ml,(39.15±8.47)ml,(57.82±6.86)%after treatment;in the elderly group,the left ventricular end-diastolic volume,left ventricular end-systolic volume,and left ventricular ejection fraction before treatment were(95.42±15.43)ml,(47.61±3.06)ml,and(46.27±9.42)%,which were(99.64±10.26)ml,(46.24±3.25)ml,and(50.26±9.84)%after treatment.There was no statistically significant difference in left ventricular end-diastolic volume before and after treatment within the two groups and in left ventricular end-systolic volume before treatment between the two groups(P>0.05).6 months after treatment,the left ventricular end-systolic volume of the two groups was lower than those of this group before treatment,and the middle-aged group was lower than that of the elderly group.All the differences were statistically significant(P<0.05).The left ventricular ejection fraction of the two groups was higher than that of this group before treatment,and the difference was statistically significant(P<0.05).6 months after treatment,the Tmsv16-SD and Tmsv12-SD of the two groups were lower than those of this group before treatment,and the difference was statistically significant(P<0.05).Conclusion Interventional therapy shows significant impr
作者
梁源
LIANG Yuan(Gaizhou Central Hospital,Gaizhou 115200,China)
出处
《中国现代药物应用》
2021年第24期40-42,共3页
Chinese Journal of Modern Drug Application
关键词
冠心病
介入治疗
不同年龄段
心肌运动
Coronary heart disease
Interventional therapy
Different ages
Myocardial motion
