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冠状动脉血管成像检查与冠状动脉造影诊断冠心病的效果分析及其与C-反应蛋白的相关性 被引量:32

Effect analysis of coronary CT angiography and coronary angiogram in diagnosis of coronary heart disease and the relationship with C-reactive protein
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摘要 目的探讨冠状动脉血管成像检查(CTA)与冠状动脉造影(CAG)在诊断冠心病的效果及其与C-反应蛋白(CRP)的相关性。方法选择疑似冠心病患者123例,分别行CTA和CAG检查,记录患者冠脉狭窄情况及CRP值,评估患者冠脉狭窄情况。探讨冠脉CTA的诊断价值。结果 CAG检出狭窄冠脉286支,CTA检出狭窄冠脉278支,CTA检查其灵敏度为95.80%,特异度为94.74%,阳性预测值为98.56%,阴性预测值为85.71%。对冠脉CTA检查结果进行分析,软斑块组(CT值≤60 HU)患者CRP值明显高于混合斑块(60 hu<CT值<130 HU)组和钙化斑块(CT值≥130 HU)组,差异有统计学意义(P<0.05)。结论冠脉CTA具有较高的特异度、灵敏度和准确度,与金标准冠脉造影检出冠心病的诊断价值相当,且CRP值能够在一定程度上判断冠心病患者斑块稳定性。 To investigate the effect of coronary CT angiography(CTA)and coronary angiogram(CAG)in the diagnosis of coronary heart disease and its correlation with C-reactive protein(CRP).From December 2015 to October 2016,123 patients with suspected coronary heart disease admitted to our hospital were enrolled in this study.They received the examinations of CTA and CAG,respectively.The status of coronary stenosis and CRP values were recorded.CTA diagnostic value was investigated.CAG detected 286 stenotic coronary arteries while CTA detected 278 stenotic coronary arteries.The sensitivity and specificity of CTA were 95.80%,and 94.74%.The PPV and NPV of CTA were 98.56%and 85.71%,respectively.The results of coronary CTA showed that CRP in soft plaque group(CT value≤60 HU)was significantly higher than that in mixed plaque group(60 Hu<CT value<130 HU)and calcified plaque group(CT value≥130 HU)(P<0.05).Coronary CTA has a high specificity,sensitivity and accuracy which are comparable to the gold standard CAG in diagnosis of coronary heart disease.CRP can assess the plaque stability of patients with coronary heart disease to some certain extents.
作者 夏欣 XIA Xin(Computed Tomography Department,Shaoyang Central Hospital,Shaoyang 422000,China)
出处 《实用医院临床杂志》 2018年第1期145-148,共4页 Practical Journal of Clinical Medicine
关键词 冠状动脉血管成像检查 冠状动脉造影 特异性 C-反应蛋白 Coronary CTA Coronary angiogram Specificity C-reactive protein
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