摘要
寨卡病毒(Zika virus,ZIKV)感染可造成宿主神经系统损伤,与胎儿头小畸形和格林-巴利综合征的发生相关。有许多针对包括ZIKV在内的黄病毒疫苗与抗病毒药物正处于研发阶段。本文总结了辅助ZIKV感染的宿主因子研究现状,有助于揭示ZIKV的感染机制。
The infection of Zika virus(ZIKV)can be detrimental to host nervous system,leading to fetal microcephaly and Guillain-Barrésyndrome.Researches are focusing on the development of vaccines and drugs targeting flaviviruses including ZIKV.This paper reviewed the present research status of the host factors which facilitates the infection of ZIKV so as to uncover the mechanism of ZIKV infection.
作者
郭娇菡(综述)
徐建青(审校)
GUO Jiao-han;XU Jian-qing(Shanghai Public Health Clinical Center,Fudan University,Shanghai 201508,China;Institute of Biomedical Science,Fudan University,Shanghai 200032,China)
出处
《复旦学报（医学版）》
CAS
CSCD
北大核心
2022年第1期144-148,158,共6页
Fudan University Journal of Medical Sciences
基金
国家自然科学基金青年项目(81901598)。
