摘要
Objective:Pancreatic cancer is one of the most aggressive digestive system malignant tumors,and its clinical diagnosis and treatment are still challenging.To further understand the current status and improve the multidisciplinary collaboration for diagnosis and treatment of pancreatic cancer in China,we conducted an online questionnaire survey on the diagnosis and treatment status of pancreatic cancer in public tertiary hospitals of China in 2021.Methods:In this cross-sectional questionnaire-based,observational study,online questionnaires with real-name authentication were used to gather data from 500 clinicians,50 pharmacists,and 1000 pancreatic cancer patients in tertiary general hospitals or cancer hospitals nationwide.Results:A total of 485 valid questionnaires were obtained from the clinicians,majority of whom were from economically better developed regions or cities of China.There were multi-disciplinary team treatment(MDT)clinics for pancreatic cancer patients in 60%of the hospitals.Minimally invasive surgeries could be performed in all the surveyed hospitals.However,open surgery was still the mainstream choice in most cases.Gemcitabine-based chemotherapy was the most popular first-line adjuvant regimen for pancreatic cancer.A total of 50 valid questionnaires were collected from pharmacists,48%of them are not satisfactory with the efficacy of the chemotherapeutic drugs,and myelosuppression,liver,and renal damage were the most concerning side effects.In total,1011 valid questionnaires were collected from the patients.Approximately,48.4%of the patients did not know about pancreatic cancer before becoming ill.Over 80%of pancreatic cancer patients reported poor to very poor health-related quality of life,and the estimated overall medical expenses were within<400,000($58823.53)in 80%of the patients.Clinicians,pharmacists,and patients believe that popularizing scientific knowledge of pancreatic cancer,constructing MDT clinics and fast-lane system,and conducting clinical research will help further improve the dia
