摘要
目的探讨多期增强多层螺旋CT(MSCT)测量的结肠癌肿瘤大小与脉管癌栓(LVI)的相关性。方法选择2016年1月至2020年12月古田县医院收治的60例结肠癌患者为研究对象,依据病理结果将患者分为LVI阴性组49例和LVI阳性组11例。采用MSCT检查并比较两组患者的肿瘤体积(Tvol)、肿瘤的最大面积(Tare)、肿瘤的最大直径(Tdia)、肿瘤长度(Tlen),应用Spearman相关分析法分析其与LVI的相关性。以病理结果作为金标准,分析肿瘤大小的测量在LVI阳性患者中的诊断效能。结果LVI阴性组患者的Tvol、Tare、Tdia及Tlen分别为(25.73±4.39)cm^(3)、(8.86±2.86)cm^(2)、(1.53±0.48)cm、(4.41±1.38)cm,明显低于阳性组的(56.69±4.83)cm^(3)、(16.03±3.28)cm^(2)、(2.02±0.57)cm、(6.21±2.03)cm,差异均有统计学意义(P<0.05);Tvol、Tare、Tdia、Tlen、N分期、T分期、分化程度、肿瘤位置圴与LVI具有明显的相关性(r=0.391,0.355,0.405,0.501,0.327,0.302,0.292,0.406,P<0.05);以病理结果作为金标准,MSCT检查中Tvol诊断LVI阳性患者的准确度、特异度、敏感度、AUC面积分别为81.37%、83.92%、68.42%、0.839,Tare的准确度、特异度、敏感度、AUC面积分别为81.37%、87.54%、63.26%、0.811,Tdia的准确度、特异度、敏感度、AUC面积分别为70.73%、71.48%、73.75%、0.768,Tlen的准确度、特异度、敏感度、AUC面积分别为69.36%、69.67%、78.93%、0.740;四者相比较,Tvol对LVI阳性患者的诊断效能明显高于Tare、Tdia、Tlen,差异有统计学意义(P<0.05)。结论结肠癌患者Tvol、Tare、Tdia、Tlen与LVI密切相关,其中Tvol的诊断效能最高。
Objective To analyze the application of multiphase enhanced MSCT in tumor size measurement of colon cancer and its correlation with lymphovascular invasion(LVI).Methods Sixty colon cancer patients in Gutian Hospital of Fujian Province from January 2016 to December 2020 were selected as the research objects.According to the pathological results,the patients were divided into LVI negative(49 cases)group and LVI positive(11 cases)group.All patients underwent multiphase enhanced multi-slice spiral CT(MSCT)examination,and tumor volume(Tvol),maximum tumor area(Tare),maximum tumor diameter(Tdia),and tumor length(Tlen)were compared within the group.The correlation between LVI and MSCT was analyzed by Spearman.Taking the pathological results as the gold standard,the diagnostic efficacy of tumor size measurement in LVI positive patients was analyzed.Results Tvol,Tare,Tdia,and Tlen in LVI negative group were(25.73±4.39)cm^(3),(8.86±2.86)cm^(2),(1.53±0.48)cm,(4.41±1.38)cm,which were significantly lower than(56.69±4.83)cm^(3),(16.03±3.28)cm^(2),(2.02±0.57)cm,(6.21±2.03)cm in LVI positive group(P<0.05).Tvol,Tare,Tdia,Tlen,N stage,T stage,degree of differentiation,and tumor location were significantly correlated with LVI(r=0.391,0.355,0.405,0.501,0.327,0.302,0.292,0.406,P<0.05).Taking pathological results as the gold standard,the accuracy,specificity,sensitivity,and AUC area in diagnosing LVI positive patients in MSCT were 81.37%,83.92%,68.42%,and 0.839 for Tvol,81.37%,87.54%,63.26%and 0.811 for Tare,70.73%,71.48%,73.75%,and 0.768 for Tdia,and 69.36%,69.67%,78.93%,and 0.740 for Tlen,respectively.The diagnostic efficacy of Tvol in LVI positive patients was significantly higher than that of Tare,Tdia,and Tlen(P<0.05).Conclusion The tumor size of Tvol,Tare,Tdia,and Tlen is closely related to LVI in patients with colon cancer,and the diagnostic efficiency of Tvol is the highest.
作者
李胜
李建业
葛建国
LI Sheng;LI Jian-ye;GE Jian-guo(Department of Medical Imaging,Gutian Hospital of Fujian Province,Ningde 352200,Fujian,CHINA;Department of Surgery,Gutian Hospital of Fujian Province,Ningde 352200,Fujian,CHINA)
出处
《海南医学》
CAS
2022年第1期83-86,共4页
Hainan Medical Journal
关键词
多层螺旋CT
肿瘤
结肠癌
脉管癌栓
相关性
诊断效能
Multi-slice spiral CT
Tumor
Colon cancer
Lymphovascular invasion
Relevance
Diagnostic efficiency
