摘要
目的探讨双歧杆菌四联活菌片联合蒙脱石散治疗小儿慢性腹泻的效果及对肠道微生态、氧化应激指标的影响。方法选取2019年7月至2021年7月我院收治的200例慢性腹泻患儿进行观察,以随机数字表法将其分为对照组和观察组,各100例。对照组采用双歧杆菌四联活菌片治疗,观察组在此基础上联合蒙脱石散治疗。比较两组治疗效果。结果观察组的治疗总有效率高于对照组(P<0.05)。治疗后,观察组的双歧杆菌、拟杆菌菌落数多于对照组,肠杆菌、肠球菌菌落数少于对照组,MDA、NO水平低于对照组(P<0.05)。结论采用双歧杆菌四联活菌片联合蒙脱石散治疗小儿慢性腹泻有助于提高临床效果,促进患儿肠道微生态改善和氧化应激反应减轻,值得推广。
Objective To explore the effect of Bifidobacteria quadruple viable bacteria tablets combined with montmorillonite powder in the treatment of chronic diarrhea in children and its influence on intestinal microecology and oxidative stress indexes.Methods A total of 200 children with chronic diarrhea treated in our hospital from July 2019 to July 2021 were selected for observation,and the children were divided into control group and observation group by random number table method,with 100 cases in each group.The control group was treated with Bifidobacteria quadruple viable bacteria tablets,and the observation group was treated with montmorillonite powder on this basis.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).After treatment,the colony numbers of Bifidobacterium and Bacteroides in the observation group were more than those in the control group,the colony numbers of Enterobacter and Enterococcus were less than those in the control group,and the levels of MDA and NO were lower than those in the control group(P<0.05).Conclusion Bifidobacteria quadruple viable bacteria tablets combined with montmorillonite powder applied in children with chronic diarrhea is helpful to improve the clinical effect,promote the improvement of intestinal microecology and reduce oxidative stress reaction,which is worthy of popularization.
作者
王惠燕
韩小莉
白雪梅
WANG Huiyan;HAN Xiaoli;BAI Xuemei(the Hospital of Chenggu County,Hanzhong 723200;3201 Hospital,Hanzhong 723000,China)
出处
《临床医学研究与实践》
2021年第36期127-129,共3页
Clinical Research and Practice
关键词
双歧杆菌四联活菌片
蒙脱石散
慢性腹泻
小儿
肠道微生态
氧化应激
Bifidobacterium quadruple viable bacteria tablets
montmorillonite powder
chronic diarrhea
children
intestinal microecology
oxidative stress
