摘要
目的分析中等强度有氧运动对高胆固醇血症患者动脉粥样硬化性心血管疾病(ASCVD)10年发病风险的影响,为预防ASCVD提供参考。方法选择2019年9月—2020年9月河北大学附属医院收治的高胆固醇血症患者为研究对象,采用随机数表法纳入干预组和对照组,2组均采用常规降脂药物治疗和健康教育,干预组增加中等强度有氧运动干预;分别于干预前和干预12周后检测血脂水平。采用ASCVD 10年发病风险评估流程评估2组患者干预后ASCVD 10年发病风险变化情况。结果干预组和对照组各纳入50例高胆固醇血症患者,年龄分别为(38.80±1.42)岁和(37.14±1.23)岁,男性分别占46.00%和40.00%。干预组干预前后高密度脂蛋白胆固醇(HDL-C)升高幅度,以及总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)和ASCVD 10年发病风险降低幅度均大于对照组(P<0.05)。结论中等强度有氧运动可通过调节血脂水平降低ASCVD 10年发病风险。
Objective To examine the effect of moderate aerobic exercise on the 10-year risk of atherosclerotic cardiovascular disease(ASCVD)in patients with hypercholesterolemia,so as to provide insights into ASCVD prevention.Methods The patients with hypercholesterolemia admitted to the Affiliated Hospital of Hebei University from September 2019 to September 2020 were recruited and randomly assigned into the intervention group and the control group using a random number table.Participants in both groups received routine lipid-lowering therapy and health education,and participants in the intervention group were given additional interventions of moderate aerobic exercise.Serum lipid levels were measured before and after 12 weeks of interventions.The 10-year risk of developing ASCVD was evaluated in both groups following interventions.Results There were 50 participants with hypercholesterolemia in each of the intervention and control groups.The mean age was(38.80±1.42)years in the intervention group and(37.14±1.23)years in the control group,and males were accounted for 46.00% and 40.00%,respectively.The increase in high-density lipoprotein cholesterol(HDL-C),the reduction in total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C)and the 10-year risk of ASCVD were all significantly greater in the intervention group than those in the control group before and after the interventions(P<0.05).Conclusion Moderate aerobic exercise may reduce the 10-year risk of ASCVD through regulating blood lipid levels.
作者
赵瑞
黄胜楠
肖暖
ZHAO Rui;HUANG Shengnan;XIAO Nuan(Department of General Practice,Affiliated Hospital of Hebei University,Baoding,Hebei 071000,China)
出处
《预防医学》
2022年第1期58-62,共5页
CHINA PREVENTIVE MEDICINE JOURNAL
基金
河北省财政厅老年病防治项目(361007)。
关键词
有氧运动
动脉粥样硬化性心血管疾病
高胆固醇血症
血脂
干预
aerobic exercise
atherosclerotic cardiovascular disease
hypercholesterolemia
blood lipid
intervention
