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A型肉毒毒素联合透明质酸钠微整形注射在重塑颜面部轮廓中的效果评价 被引量:5

Evaluation of Effect of Botulinum Toxin Type A Combined with Sodium Hyaluronate Microplastic Injection on Reshaping Facial Contours
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摘要 目的:分析A型肉毒毒素(保妥适)联合透明质酸钠(玻尿酸)微整形注射在重塑颜面部轮廓中的效果。方法:回顾性分析2018年7月-2019年9月于笔者医院行面部轮廓微整形注射的118例就医者的临床资料。从采用A型肉毒毒素注射联合自体脂肪填充的就医者中随机选取59例设为对照组,从采用A型肉毒毒素注射联合透明质酸钠填充的就医者中随机选取59例纳入观察组。比较两组就医者注射前及注射后3个月时的面下部轮廓变化[面下部宽度(WLF)、面下部长度(LLF)、面下部宽度与长度比值(WLF/LLF)、面中长度、下颏夹角∠AOB]、除皱塑形疗效及不良反应发生情况;比较两组就医者注射术后6个月时的整形满意度。结果:两组就医者术后3个月时的面部WLF、WLF/LLF、∠AOB值较术前明显降低,但观察组与对照组比较无明显差异(P>0.05),而两组就医者的LLF及面中部长度值于术前术后无明显变化(P>0.05);术后3个月时,观察组就医者的除皱疗效与对照组间无明显差异(Z=1.492,P=0.137);两组患者术后3个月期间不良反应发生率无明显差异(P>0.05);术后6个月时,对照组就医者的满意度评分及满意度评价(Z=2.114,P=0.035)显著优于观察组(P<0.05)。结论:A型肉毒毒素注射联合自体脂肪填充或联合透明质酸钠填充均可有效重塑就医者的面部轮廓,改善面部皱纹严重程度,且安全性良好。虽然A型肉毒毒素注射联合自体脂肪填充治疗的术后满意度较高,但其自身肿胀麻醉取脂的治疗模式,令多数就医者更倾向于使用透明质酸钠填充治疗。故临床应根据就医者的意愿,选择合适的干预方式。 Objective To analyze the effect of botulinum toxin type A(Botox)combined with sodium hyaluronate microplastic injection on reshaping facial contours.Methods A retrospective analysis was performed on the clinical data of 118 beauty seekers who came to our hospital for facial contouring between July 2018 and September 2019.59 cases were randomly selected from the seekers who received botulinum toxin type A injection combined with autologous fat filling as control group,and 59 cases were randomly selected from the seekers who received botulinum toxin type A injection combined with sodium hyaluronate filling and were included in observation group.The lower face contour changes[width of lower face(WLF),length of lower face(LLF),ratio of width of lower face and length of lower face(WLF/LLF),mid-face length,lower mentum angle∠AOB],efficacy of wrinkle removal and occurrence of adverse reactions were compared between the two groups before surgery and at 3 months after surgery.The plastic satisfaction of the two groups of seekers was compared at 6 months after surgery.Results At 3 months after surgery,the facial WLF,WLF/LLF and∠AOB of the two groups of seekers were significantly lower than those before surgery,but there were no significant differences between observation group and control group(P>0.05),but there were no significant changes in LLF and mid-face length in the two groups of seekers before and after surgery(P>0.05).At 3 months after surgery,no significant difference was found in efficacy of wrinkle removal between observation group and control group(Z=1.492,P=0.137).There were no significant differences in the incidence rates of adverse reactions between the two groups during 3 months after surgery(P>0.05).At 6 months after surgery,the satisfaction score and satisfaction evaluation(Z=2.114,P=0.035)of seekers in control group were significantly better than those in observation group(P<0.05).Conclusion Botulinum toxin type A injection combined with autologous fat filling or combined with sodium hyaluronate fi
作者 仲元奎 梁方 崔璐 南建刚 ZHONG Yuan-kui;LIANG Fang;CUI Lu;NAN Jian-gang(Department of Plastic Surgery,the Second People’s Hospital of Xining,Xining 810003,Qinghai,China)
出处 《中国美容医学》 CAS 2021年第12期26-30,共5页 Chinese Journal of Aesthetic Medicine
关键词 A型肉毒毒素 自体脂肪填充 透明质酸钠 颜面部轮廓 除皱塑形疗效 不良反应 整形满意度 botulinum toxin type A autologous fat filling sodium hyaluronate facial contours wrinkle removal efficacy adverse reactions plastic satisfaction
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