摘要
目的探讨子宫内膜癌患者腹腔镜手术后下肢深静脉血栓形成的影响因素。方法收集2016年1月至2020年7月在四川省妇幼保健院接受腹腔镜手术的388例子宫内膜癌患者的临床资料。根据术后下肢深静脉血栓形成的发生情况分为发生组(n=47)和未发生组(n=341)。分析子宫内膜癌患者腹腔镜术后下肢深静脉血栓形成的影响因素。结果单因素分析结果显示,年龄>45岁、体重指数(BMI)>24 kg/m2、职业属性以体力为主、手术时间>180 min、术中失血量>200 ml、术后行物理抗凝治疗、术后卧床时间>24 h、有淋巴结转移、肿瘤分化程度为低分化、肿瘤国际妇产科联盟(FIGO)分期为Ⅲ期的子宫内膜癌患者术后下肢深静脉血栓形成的发生率高于年龄≤45岁、BMI≤24 kg/m2、职业属性以脑力为主、手术时间≤180 min、术中失血量≤200 ml、术后未行物理抗凝治疗、术后卧床时间≤24 h、无淋巴结转移、肿瘤分化程度为中高分化、肿瘤FIGO分期为Ⅰ~Ⅱ期的子宫内膜癌患者,差异均有统计学意义(P<0.05)。多因素分析结果显示,年龄、手术时间、术中失血量、淋巴结转移情况、肿瘤分化程度、肿瘤FIGO分期均是子宫内膜癌患者腹腔镜手术后发生下肢深静脉血栓形成的危险因素(P<0.05)。结论子宫内膜癌患者在行腹腔镜手术后,具有一定的下肢深静脉血栓形成风险。手术治疗及部分病理因素均成为该类患者下肢深静脉血栓形成的独立影响因素,临床中需要给予针对性的预防及控制措施。
Objective To investigate the influence factors of lower extremity deep venous thrombosis after laparoscopic surgery in patients with endometrial cancer.Method The clinical data of 388 patients with endometrial cancer who underwent laparoscopic surgery in Sichuan Maternal and Child Health Hospital from January 2016 to July 2020 were collected.According to the occurrence of deep venous thrombosis of the lower extremities after the operation,they were divided into an occurrence group(n=47)and a non-occurring group(n=341).The influence factors of deep venous thrombosis of lower extremities in patients with endometrial cancer after laparoscopic surgery were analyzed.Result The univariate analysis showed that the incidence rate of postoperative deep venous thrombosis of lower extremities in patients with age>45 years old,body mass index(BMI)>24 kg/m2,occupational attributes were mainly physical strength,operation time>180 min,intraoperative blood loss>200 ml,postoperative physical anticoagulant therapy,postoperative bed rest time>24 h,lymph node metastasis,poorly differentiated tumor,International Federation of Gynecology and Obstetrics(FIGO)stage III was higher than those patients with age≤45 years old,BMI≤24 kg/m2,professional attributes were mainly mental,operation time≤180 min,intraoperative blood loss≤200 ml,no postoperative physical anticoagulant therapy,postoperative bed time≤24 h,no lymph node metastasis,medium and high differentiated tumor,FIGO stage I-II(P<0.05).The results of multivariate analysis showed that age,operation time,intraoperative blood loss,lymph node metastasis,tumor differentiation FIGO stage was the risk factor of lower extremity deep venous thrombosis in patients with endometrial cancer after laparoscopic surgery(P<0.05).Conclusion Patients with endometrial cancer have a certain risk of lower extremity deep venous thrombosis after laparoscopic surgery.Surgical treatment and some pathological factors have become the independent influencing factors of lower extremity deep venous thro
作者
王小琦
雷碧波
高亚
薛龙
张丽峰
Wang Xiaoqi;Lei Bibo;Gao Ya;Xue Long;Zhang Lifeng(Department of Intensive Care Unit,Sichuan Maternal and Child Health Hospital,Chengdu 610041,Sichuan,China;Department of Anesthesiology,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,Sichuan,China;Department of Vascular Surgery,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,Sichuan,China)
出处
《血管与腔内血管外科杂志》
2021年第9期1099-1104,共6页
Journal of Vascular and Endovascular Surgery
关键词
子宫内膜癌
腹腔镜
下肢
深静脉血栓形成
恶性肿瘤
淋巴结转移
endometrial cancer
laparoscope
lower extremity
deep venous thrombosis
malignant tumor
lymph node metastasis
