摘要
柚皮素降血糖、降血脂、抗肿瘤、抗菌、抗氧化等作用的活性成分。以柚皮素与盐酸羟胺反应得到4-肟基柚皮素,然后与酰氯或乙酸酐通过选择性酯化合成了6种酰化柚皮素肟3a-3f,其结构经核磁氢谱和高分辨质谱进行了表征。
Naringenin is an active ingredient with hypoglycemic,hypolipidemic,antitumor,antibacterial and antioxidant effects.In this paper,six acylated naringenin oximes were synthesized via the reaction of naringenin with hydroxylammonium chloride and then selective esterification reaction with acyl chloride or acetic anhydride,their structures were characterized by ^(1)H-NMR and MS.
作者
尹民海
汤希雁
刘志平
黄燕敏
YIN Min-hai;TANG Xi-yan;LIU Zhi-ping;HUANG Yan-min(College of Chemistry and Material,Nanning Normal University,Nanning Guangxi 530001,China)
出处
《辽宁化工》
CAS
2021年第12期1778-1780,1784,共4页
Liaoning Chemical Industry
基金
广西科学自然科学基金(项目编号:2020GXNSFAA159096、2014GXNSFBA118033)。
关键词
柚皮素
乙酰化
肟
Naringenin
Acetylated
Oximes
