摘要
【目的】探讨加味扁豆薏米粥对51例脾虚湿盛型原发性高脂血症患者的疗效以及血清同型半胱氨酸和游离脂肪酸水平的影响。【方法】筛选2019年7月至2021年4月在我院就诊的脾虚湿盛型原发性高脂血症患者102例,采取随机数字表法分为对照组(n=51)和治疗组(n=51)。对照组给予辛伐他汀片,治疗组在对照组的基础上给予加味扁豆薏米粥治疗。两组连续治疗12周。比较两组血脂指标、脾虚湿盛证症状评分、临床疗效以及同型半胱氨酸和游离脂肪酸水平。【结果】治疗后,治疗组的胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)改善明显优于对照组,脾虚湿盛证症状评分明显低于对照组(P<0.01);治疗组的总有效率高于对照组(P<0.05);治疗后,两组血清同型半胱氨酸和游离脂肪酸明显下降,且治疗组血清同型半胱氨酸和游离脂肪酸水平改善更明显(P<0.01)。【结论】在西医常规药物治疗基础上,加味扁豆薏米粥可改善脾虚湿盛型原发性高脂血症患者的血脂水平和中医证候,提高治疗效果,且可调节同型半胱氨酸和游离脂肪酸水平。
【Objective】To investigate the effect of modified lentil barley porridge on 51 patients with primary hyperlipidemia of spleen deficiency and dampness excess type and the level of serum homocysteine and free fatty acid.【Methods】The 102 patients with primary hyperlipidemia of spleen deficiency and dampness excess type treated in our hospital from July 2019 to April 2021 were selected and randomly divided into control group(n=51)and treatment group(n=51).The control group was given simvastatin tablets,and the treatment group was given modified lentil barley porridge on the basis of the control group.The two groups were treated for 12 weeks.The blood lipid indexes,symptom score of spleen deficiency and dampness excess syndrome,clinical curative effect and the levels of homocysteine and free fatty acid were compared between the two groups.【Results】After treatment,the improvement of cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C)in the treatment group was significantly better than that in the control group,and the symptom score of spleen deficiency dampness excess syndrome was significantly lower than that in the control group(P<0.01);The total effective rate of the treatment group was higher than that of the control group(P<0.05);After treatment,the levels of serum homocysteine and free fatty acid decreased significantly in the two groups,and the levels of serum homocysteine and free fatty acid improved more significantly in the treatment group(P<0.01).【Conclusion】On the basis of conventional western medicine treatment,modified lentil barley porridge can improve the blood lipid level and TCM syndrome of patients with primary hyperlipidemia of spleen deficiency and dampness excess type,improve the treatment effect,and adjust the levels of homocysteine and free fatty acid.
作者
袁怿
李璐
YUAN Yi;LI Lu(Nutrition Department,Beijing Hospital of Traditional Chinese Medicine,Beijing 100010,China)
出处
《武警后勤学院学报（医学版）》
CAS
2021年第12期36-37,40,共3页
Journal of Logistics University of PAP（Medical Sciences）
关键词
高脂血症
加味扁豆薏米粥
脾虚湿盛型
同型半胱氨酸
游离脂肪酸
Hyperlipidemia
Modified lentil barley porridge
Spleen deficiency dampness excess type
Homocysteine
Free fatty acids
