摘要
目的观察中药沐足治疗非糜烂性胃食管反流病(Non-erosive gastrooesophageal reflux disease,NERD)伴焦虑状态的临床疗效,以期为临床治疗NERD改善焦虑状态提供有效治疗方法。方法选取2016年1月—2017年12月期间在广东省中医院大学城医院消化内科门诊及住院部治疗的NERD患者60例。采用随机数字表法随机分为治疗组和对照组,每组各30例。对照组按照NERD的常规药物治疗(不使用抗焦虑药物),治疗组在对照组基础上给予中药沐足治疗。两组患者均连续治疗7 d后,观察比较两组患者焦虑量表(Hamilton anxiety scale,HAMA)评分、中医证候量表评分,血浆胃动素(Motilin,MLT)含量及不良反应发生情况。结果治疗后治疗组总有效率为93.33%(28/30),对照组总有效率为90.00%(27/30),两组比较,差异有统计学意义(P<0.05)。治疗后两组患者中医证候量表评分明显低于治疗前,差异有统计学意义(P<0.05);且治疗组治疗后中医证候量表评分明显低于对照组,两组比较,差异有统计学意义(P<0.05)。治疗后两组患者HAMA评分明显低于治疗前,、MLT含量明显高于治疗前,差异有统计学意义(P<0.05);且治疗组治疗后HAMA评分明显低于对照组,MLT含量明显高于对照组,两组比较,差异有统计学意义(P<0.05)。两组患者治疗过程中均未出现不良反应。结论中药沐足可有效改善胃食管反流病的临床症状及焦虑状态,值得临床应用。
Objective To observe the treatment of non-erosive Gastrooesophageal Reflux Disease(NERD)with anxiety with traditional Chinese medicine foot foot massage,in order to provide effective treatment for clinical treatment of NERD to improve anxiety.Methods 60 patients with non erosive gastroesophageal reflux disease treated in the outpatient and inpatient department of Gastroenterology of university town hospital of Guangdong Hospital of traditional Chinese medicine from January 2016 to December 2017 were selected.The patients were randomly divided into treatment group and control group with 30 cases in each group.The control group was given conventional drug treatment according to NERD(without the use of anti-anxiety drugs),and the treatment group was given traditional Chinese medicine on the basis of the control group.After 7 days of continuous treatment for both groups of patients,the Hamilton Anxiety Scale(HAMA)scores,TCM syndrome scale scores,clinical symptoms improvement,plasma motilin(MLT)content,and adverse reactions between the two groups were observe and compare.Results After treatment,the total effective rate of the treatment group was 93.33%(28/30),and the total effective rate of the control group was 90.00%(27/30).The difference between the two groups was statistically significant(P<0.05).After treatment,the scores of the TCM Syndrome Scale of the two groups of patients were significantly lower than those before the treatment,and the difference was statistically significant(P<0.05);and the scores of the TCM Syndrome Scale of the treatment group after treatment were significantly lower than those of the control group.There was a difference between the two groups There is statistical significance(P<0.05).After treatment,the HAMA score of the two groups of patients was significantly lower than before treatment,and the MLT content was significantly higher than before treatment,the difference was statistically significant(P<0.05);and the HAMA score of the treatment group after treatment was significantly lower
作者
陈君千
林晓丰
郑欢
黎颖婷
黄马养
钟卓丹
CHEN Jun-qian;LIN Xiao-feng;ZHENG Huan;LI Ying-ting;HUANG Ma-yang;ZHONG Zhuo-dan(Department of Spleen and Stomach Diseases,University Town Hospital,Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou Guangdong 510006;The Second Clinical School of Guangzhou University of Traditional Chinese Medicine,Guangzhou Guangdong 510006)
出处
《世界中西医结合杂志》
2021年第10期1865-1868,共4页
World Journal of Integrated Traditional and Western Medicine
基金
广东省中医药局科研项目(20162067)。
关键词
中药沐足
非糜烂性胃食管反流病
焦虑
炎性因子
Foot Bathing with Traditional Chinese Medicine
NERD
Anxiety
Inflammatory Factors
