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利妥昔单抗治疗难治性肾病综合征伴大量胸腔积液一例 被引量:1

Rituximab in the treatment of refractory nephrotic syndrome with massive pleural effusion: one case report
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摘要 病例资料患者,女,65岁,因"反复双下肢水肿1年半,加重1个月"于2020年6月15日入院。患者1年半前无明显诱因下出现双下肢对称凹陷性水肿,伴尿泡沫增多,无尿色及尿量异常,至某战区总医院就诊,查尿蛋白2.7 g/24 h,抗M型磷脂酶A2受体(phospholipase A2 receptor,PLA2R)抗体114.04 RU/mL,血清白蛋白27 g/L,排除其他继发性疾病,临床诊断为"特发性膜性肾病"。
作者 张朔凡 汤日宁 施璇 高月明 张晓良 刘必成 Zhang Shuo-fan;Tang Ri-ning;Shi Xuan;Gao Yue-ming;Zhang Xiao-liang;Liu Bi-cheng(Department of Nephrology,Zhongda Hospital,Institute of Nephrology,School of Medicine,Southeast University,Nanjing 210009,China;Department of Nephrology,Lishui Branch,Zhongda Hospital,Southeast University,Nanjing 211200,China)
出处 《临床肾脏病杂志》 2021年第12期1052-1054,共3页 Journal Of Clinical Nephrology
基金 国家自然科学基金(31571186、81770735) 江苏省卫计委科教强卫重点医学人才资助(ZDRCA2016079) 江苏省高层次人才“六个一工程”拔尖人才项目(LGY2018097)。
关键词 利妥昔单抗 难治性肾病综合征 膜性肾病 Rituximab Refractory nephrotic syndrome Membranous nephropathy
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