摘要
目的分析诱发子痫前期(PE)孕妇发生胎盘早剥的相关危险因素研究及对其母婴结局的影响。方法选择2016年3月至2018年3月PE患者294例作为研究对象,根据是否合并胎盘早剥分为对照组(合并胎盘早剥)和研究组(不合并胎盘早剥)。比较两组患者的不良母婴结局发生率。收集、检测并比较两组患者一般资料和血清指标。并使用Logistic多元回归分析法分析胎盘早剥的危险因素。结果研究组不良母婴结局的发生率显著高于对照组(P<0.05)。研究组的收缩压、舒张压、羊水过少比例、总胆红素、尿氮素、血肌酐均显著高于对照组(P<0.05),而研究组血小板、纤维蛋白原显著低于对照组(P<0.05)。多因素Logistic回归分析显示,收缩压>155 mmHg、舒张压>103 mmHg、羊水过少、总胆红素>75 umol/L、尿氮素>6.0 mmol/L、血肌酐>85 mmol/L、血小板<160×10^(9)/L、纤维蛋白原<5 g/L是PE患者发生胎盘早剥的危险因素。结论对于以上几种指标中,凝血功能和血清尿氮素、血肌酐检测较为便捷,可作为PE发生胎盘早剥的诊断参考。
Objective To analyze the risk factors associated with placental abruption in pregnant women with preeclampsia(PE)and its effects on maternal and fetal outcomes.Methods From March 2016 to March 2018,294 patients with PE were selected as subjects,and were divided into control group(combined placental premature rupture)and study group(without premature rupture of the placenta)according to whether or not combined with premature rupture of placenta.The incidence of adverse maternal and fetal outcomes was compared between the two groups.General data and serum indicators were collected,tested and compared between the two groups.Logistic multiple regression analysis was used to analyze the risk factors of placental abruption.Results The incidence of adverse maternal and infant outcomes in the study group was significantly higher than that in the control group(P<0.05).The systolic blood pressure,diastolic blood pressure,oligohydramnios ratio,total bilirubin,urinary nitrogen and serum creatinine were significantly higher in the study group than in the control group(P<0.05).The platelet and fibrinogen in the study group were significantly lower than the control group(P<0.05).Multivariate logistic regression analysis showed systolic blood pressure>155 mmHg,diastolic blood pressure>103 mmHg,oligohydramnios,total bilirubin>75 umol/L,urinary nitrogen>6.0 mmol/L,serum creatinine>85 mmol/L,platelet<160×10^(9)/L and fibrinogen<5 g/L are risk factors for placental abruption in PE patients.Conclusion For the above indicators,coagulation function and serum urinary nitrogen,serum creatinine detection is more convenient,can be used as a reference for the diagnosis of placental abruption of PE.
作者
靳金红
赵伟
JIN Jin-hong;ZHAO Wei(Department of Obstetrics,Jiaozuo People’s Hospital,Jiaozuo 454000 China)
出处
《内蒙古医学杂志》
2021年第12期1429-1431,共3页
Inner Mongolia Medical Journal
基金
河南省自然科学基金项目(编号:2019YX6874)。
关键词
子痫前期
胎盘早剥
危险因素
preeclampsia
placentae abruptio
risk factor
