摘要
脓毒症是宿主对感染反应失调所致的危及生命的器官功能障碍,病情进展迅速,病死率高,是重症监护病房(ICU)患者死亡的重要原因之一。脓毒症的具体发病机制尚不十分清楚,机体的早期炎症反应、免疫功能障碍及各器官病理改变在其发病过程中起着十分重要的作用。现针对脓毒症病理生理状态、治疗进展及未来方向等方面进行综述,以期对早期预防脓毒症发生及提高疗效提供帮助。
Sepsis is a life-threatening organ dysfunction causerd by the maladjusted response of the host to infection,its rapid progression and high mortality are one of the important causes of death in intensive care unit(ICU)patients.The specifie pathogenesis of sepsis is not well understood,and the rarly inflammatory response.immune dysfunction and pathological changes of various organs in the organism play a very imporlant role in its pathogenesis.This article reviews the patho-physiological status.treatment progress and future direction of sepsis in order to provide help for early prevention of its ocurrenre and improvement of therapeutie efficacy.
作者
麦丽帕特·伊力艾克拜尔
徐桂萍
Mailipate Yiliaikebaier;Xu Guiping(Graduate School,Xinjiang Medical Unirersity,Urumqi 830011,Xinjiang Uygur Autonomous Region,China;Department of Anesthesiology,People's Hopital of Xinjiang Uygur Autonomous Region,Urumqi 830002,Xinjiang Uygur Autonomous Region,China)
出处
《中国中西医结合急救杂志》
CAS
CSCD
北大核心
2021年第4期505-508,共4页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
国家自然科学基金(81860345)。
关键词
脓毒症
炎症反应
免疫抑制
液体复苏
抗菌药物
Sepsis
Infammatory reaction
Immunosuppression
Fluid rsuscitation
Anihiotie
