摘要
肝肺综合征(hepatopulmonary syndrome,HPS)是晚期肝病常见的肺部并发症,是在急慢性肝病或门静脉高压基础上,肺内血管扩张引起的肺通气/灌注比例失调,临床常表现为呼吸困难和低氧血症。肝肺综合征早期不易诊断、治疗手段有限,严重影响患者的生存率和生存质量。本文对肝肺综合征的病因、发病机制、临床表现、诊断和治疗等进行概述,以期加深对肝肺综合征的理解,提高其诊疗水平。
Hepatopulmonary syndrome(HPS)is a common pulmonary complication of advanced liver disease.The disturbance of pulmonary ventilation/blood perfusion due to intrapulmonary vascular dilatations on the basis of acute/chronic liver disease or portal hypertension leads to dyspnea and hypoxemia.The early diagnosis rate of HPS is low,and the treatment is limited,which seriously affects the survival rate and quality of life of patients.In this article,we summary pathogenesis,clinical manifestations,diagnosis and treatment progress of HPS,in order to improve the clinical understanding and diagnosis level of HPS.
作者
赵凯
田德安
Kai ZHAO;De-An TIAN(Department of Gastroenterology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)
出处
《医学新知》
CAS
2021年第6期472-477,共6页
New Medicine
基金
国家自然科学基金项目(81974071)。
关键词
肝肺综合征
肺血管扩张
诊断
治疗
Hepatopulmonary syndrome
Intrapulmonary vascular dilatations
Diagnosis
Treatment
