摘要
目的探讨结直肠癌NO.253淋巴结转移的危险因素,为临床决策NO.253淋巴结清扫提供参考。方法采用回顾性研究方法,收集于2017年9月至2019年4月期间在河北医科大学第四医院外二科住院并行根治术的205例结直肠癌患者资料,选取可能影响NO.253淋巴结转移的临床病理因素进行危险因素分析。结果单因素分析显示,肿瘤距肛缘距离、术前血清癌胚抗原(CEA)和糖类抗原19-9(CA19-9)水平、T分期、脉管瘤栓、神经受侵与NO.253淋巴结转移相关(P<0.05);多因素logistic回归分析显示,脉管瘤栓是NO.253淋巴结转移的独立危险因素(OR=8.506,95%CI:1.841~39.302)。结论脉管瘤栓是结直肠癌患者NO.253淋巴结转移的独立危险因素,是选择性NO.253淋巴结清扫的重要参考因素。
Objective To explore the risk factors related to No.253 lymph node metastasis,in order to provide reference for No.253 lymph node dissection. Methods The data of 205 patients with colorectal cancer who underwent radical resection in our department from September 2017 to April 2019 was retrospectively analyzed. The clinicopathological factors that may affect lymph node metastasis of No.253 were selected for risk factor analysis.Results Univariate analysis data showed that No.253 lymph node metastasis was significantly related to the distance from the tumor to the anal margin,preoperative serum CEA,preoperative serum CA19-9,T stage,vascular tumor thrombus and nerve invasion(P<0.05). Multivariate Logistic regression analysis results demonstrated that vascular tumor thrombus[OR=8.506,95%CI(1.841,39.302)]was an independent risk factor for No.253 lymph node metastasis. Conclusion Vascular tumor thrombus is an independent risk factor for No.253 lymph node metastasis. It could be an important reference factor for selective No.253 lymph node dissection.
作者
张建锋
高相鑫
武雪亮
马洪庆
胡旭华
孟泽松
张鹏飞
唐宇杰
王贵英
ZHANG Jianfeng;GAO Xiangxin;WU Xueliang;MA Hongqing;HU Xuhua;MENG Zesong;ZHANG Pengfei;TANG Yujie;WANG Guiying(The Second Department of General Surgery,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China;不详)
出处
《实用医学杂志》
CAS
北大核心
2021年第22期2893-2897,共5页
The Journal of Practical Medicine
基金
河北省医学科学研究重点课题计划(编号:20210134)。
