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双水平正压通气联合肺泡表面活性物质对新生儿呼吸窘迫综合征的疗效分析 被引量:2

Efficacy Analysis of Double-level Positive Pressure Ventilation Combined with Alveolar Surfactant on Neonatal Respiratory Distress Syndrome
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摘要 目的:观察联合正压通气对新生儿呼吸窘迫综合征(NRDS)的疗效。方法:选取2018年3月至2019年3月于新乡市中心医院就诊的120例患儿进行观察,均为NRDS,并依据不同治疗方式分为两组,对照组60例予以双水平正压通气治疗,观察组60例予以双水平正压通气联合肺泡表面活性物质治疗,比较两组患儿疗效。结果:治疗24 h后观察组的动脉血氧分压(PaO_(2))、动脉血氧饱和度(SaO_(2))、血浆二氧化碳总量(TCO_(2))高于对照组,动脉血氧分压(PaCO_(2))低于对照组,差异具有统计学意义(P<0.05)。两组治疗不良反应发生率比较,观察组明显低于对照组,差异具有统计学意义(P<0.05)。结论:临床在治疗NRDS时予以患儿双水平正压通气联合肺泡表面活性物质,临床疗效显著,并发症也较少,安全有效。 Objective To observe the efficacy of combined positive pressure ventilation on neonatal respiratory distress syndrome(NRDS).Methods 120 cases of NRDS were treated from March 2018 to March 2019 were observed and divided into two groups according to different treatment methods.60 patients were treated with double-level positive pressure ventilation and 60 patients with double-level positive pressure ventilation combined with alveolar surfactant to compare the efficacy of the two groups.Results Respiratory index before and after treatment between the two groups(P>0.05).The observation group was significantly better compared to the control group(P<0.05);the incidence of adverse treatment was significantly lower than the control group and significantly significant(P<0.05).Conclusion Double-level positive pressure ventilation in children with NRDS has a significant clinical effect,fewer complications,safety and effectiveness.
作者 原超 王园秀 邢二庆 刘倩 YUAN Chao;WANG Yuan-xiu;XING Er-qing;LIU Qian(Xinxiang Central Hospital,Henan Xinxiang 453000)
机构地区 新乡市中心医院
出处 《深圳中西医结合杂志》 2021年第18期133-135,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词 新生儿呼吸窘迫综合征 双水平正压通气 肺泡表面活性物质 Neonatal respiratory distress syndrome Double-level positive pressure ventilation Alveolar surfactant
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