摘要
目的了解江苏省常州市金坛区8~17周岁学生甲状腺结节流行状况,探讨未成年学生甲状腺结节发生的危险因素。方法2018年9月,在金坛区抽取2所中小学校、1所普通高中和1所职业高中作为调查地点,抽取8~17周岁学生作为调查对象,进行问卷调查、体格检查、甲状腺B超检查;同时,采集学校及所在乡镇饮用水水样检测水碘,采集学生尿样及家庭食用盐盐样检测尿碘、盐碘。采用多因素logistic回归分析可能影响甲状腺结节发生的相关因素。结果共调查学生725人,其中,男生359人(49.5%),女生366人(50.5%)。4所学校各采集水样2份,水碘均值分别为0.3、8.5、0.2和0.2μg/L;4所学校所在乡镇各采集水样2份,水碘均值分别为6.8、8.1、4.8和3.7μg/L。共采集学生尿样725份,尿碘中位数为209.92μg/L,范围为8.60~932.00μg/L。共采集学生家庭食用盐盐样725份,盐碘含量为(23.75±7.10)mg/kg,范围为0.00~60.30 mg/kg,95.0%(689/725)的学生家庭食用碘盐。共检查725名学生甲状腺,检出甲状腺肿大22人,肿大率为3.0%;检出甲状腺结节155人,检出率为21.4%。男、女生甲状腺结节检出率分别为20.9%(75/359)、21.9%(80/366);近1个月参加及未参加课外补习/兴趣班学生甲状腺结节检出率分别为28.2%(71/252)、17.8%(84/473)。多因素logistic回归分析结果显示,女生和近1个月参加课外补习/兴趣班是甲状腺结节发生的独立危险因素[比值比(OR)=2.057、2.538,95%置信区间(CI):1.226~3.451、1.532~4.204,P均<0.05]。结论金坛区8~17周岁学生甲状腺结节检出率处于较高水平,女生和近1个月参加课外补习/兴趣班是甲状腺结节发生的独立危险因素。
Objective To investigate the prevalence of thyroid nodules among students aged 8-17 years in Jintan District,Changzhou City,Jiangsu Province,and to explore the risk factors of thyroid nodules among underage students.Methods In September 2018,two primary and middle schools,one ordinary high school and one vocational high school in Jintan District were selected as the survey sites.Students aged 8-17 years were selected as the survey subjects,and questionnaire survey,physical examination and thyroid ultrasound examination were conducted.At the same time,drinking water samples from schools and towns were collected to test water iodine,and urine samples from students and family salt samples were collected to test urinary iodine and salt iodine.Multivariate logistic regression was used to analyze related factors that may affect the occurrence of thyroid nodules.Results A total of 725 students were surveyed,including 359(49.5%)boys and 366(50.5%)girls.Two water samples were collected from each of the four schools,and the mean values of water iodine were 0.3,8.5,0.2 and 0.2μg/L,respectively;two water samples were collected from each of the towns where the four schools were located,and the mean values of water iodine were 6.8,8.1,4.8 and 3.7μg/L,respectively.A total of 725 urine samples were collected,and the median urinary iodine was 209.92μg/L,ranging from 8.60 to 932.00μg/L.A total of 725 edible salt samples were collected from students'families,and the salt iodine content was(23.75±7.10)mg/kg,ranging from 0.00 to 60.30 mg/kg,and 95.0%(689/725)of students'families ate iodized salt.A total of 725 students were examined for thyroid gland,and 22 were diagnosed with goiter,with an enlargement rate of 3.0%;and 155 were diagnosed with thyroid nodules,with a detection rate of 21.4%.The detection rates of thyroid nodules in boys and girls were 20.9%(75/359)and 21.9%(80/366),respectively;the detection rates of thyroid nodules in students who participated and did not participate in extracurricular tuition/interest classes i
作者
郭燕丽
叶云杰
谢轶青
戴伟
Guo Yanli;Ye Yunjie;Xie Yiqing;Dai Wei(Department for Schistosomiasis,Parasitic and Endemic Disease Control,Changzhou Center for Disease Control and Prevention,Changzhou 213022,China;Institute of Environment and Health(Institute for Endemic Disease Control),Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,China;Department for Schistosomiasis,Parasitic and Endemic Disease Control,Jintan District Center for Disease Control and Prevention,Changzhou 213200,China)
出处
《中华地方病学杂志》
CAS
北大核心
2021年第11期906-913,共8页
Chinese Journal of Endemiology
基金
江苏省血地寄防科研课题(X201819)。
关键词
学生
甲状腺结节
检出率
影响因素
Students
Thyroid nodule
Detection rate
Influencing factors
