摘要
目的研究医院住院患者耐甲氧西林金黄色葡萄球菌(MRSA)感染特征及耐药性变化趋势,为有效控制MRSA医院感染提供依据。方法采用回顾性分析方法,对某医院住院患者感染MRSA特征及其耐药性变迁进行调查与分析。结果共分离出金黄色葡萄球菌1337株,其中含MRSA 428株,检出率为31.68%。MRSA科室分布居前3位的是神经外科、重症监护病房和保健病房,构成比依次为21.73%、17.29%和15.42%。MRSA主要分离自痰液和分泌物,构成比分别为40.65%和28.97%。MRSA对万古霉素、利奈唑胺、奎奴普汀/达福普汀和替加环素敏感,对头孢西丁、苯唑西林和青霉素耐药率均在90%以上。结论该医院住院患者感染的金黄色葡萄球菌中MRSA占比较高,以呼吸道感染为主,应加强耐药菌监测和抗菌药物管理。
Objective To study the characteristics of methicillin-resistant Staphylococcus aureus(MRSA)infection and the trend of drug resistance in hospitalized patients,so as to provide evidence for the effective control of MRSA nosocomial infections.Methods A retrospective analysis method was used to investigate and analyze the characteristics of MRSA infection and the changes in drug resistance among inpatients in a hospital.Results A total of 1337 strains of Staphylococcus aureus were isolated,including 428 strains of MRSA,with a detection rate of 31.68%.The top three departments of MRSA distribution were neurosurgery,intensive care unit,and health ward,with the composition ratios being 21.73%,17.29%and 15.42%.MRSA was mainly isolated from sputum and secretions,with a composition ratio of 40.65%and 28.97%,respectively.MRSA was sensitive to vancomycin,linezolid,quinupristin/dalfopristin and tigecycline,and the resistance rates to cefoxitin,oxacillin and penicillin were all above 90%.Conclusion The proportion of MRSA in Staphylococcus aureus infections in the inpatients of this hospital are relatively high,and respiratory tract is the main infection site.The monitoring of drug-resistant bacteria and the management of antibacterial drugs should be strengthened.
作者
刘卫平
任伟
王萌
赵宇平
邢慧敏
白海波
张帅
许彬彬
杨永芳
张凯
李昊雪
郭天慧
海云婷
杨丽芳
LIU Wei-ping;REN Wei;WANG Meng;ZHAO Yu-ping;XING Hui-min;BAI Hai-bo;ZHANG Shuai;XU Bin-bin;YANG Yong-fang;ZHANG Kai;LI Hao-xue;GUO Tian-hui;HAI Yun-ting;YANG Li-fang(Inner Mongolia People's Hospital,Hohhot Inner Mongolia 010010,China)
出处
《中国消毒学杂志》
CAS
2021年第11期846-849,共4页
Chinese Journal of Disinfection
基金
传染病预防控制国家重点实验室自主研究课题(2019SKLID305)
内蒙古自治区自然科学基金项目〔2017MS(LH)0845〕。
关键词
耐甲氧西林金黄色葡萄球菌
耐药性
医院感染
methicillin-resistant Staphylococcus aureus
drug resistance
nosocomial infection
