摘要
目的探讨硫酸镁复合罗哌卡因行腹横肌平面(TAP)阻滞对腹腔镜子宫切除术术后镇痛效果的影响。方法选取2019年11月—2020年11月收治的58例行腹腔镜子宫切除术患者为研究对象,58例患者随机分为对照组(n=29)和研究组(n=29),两组均行双侧TAP阻滞,对照组每侧注射20 mL罗哌卡因(浓度0.375%)+2 mL生理盐水,研究组每侧注射20 mL罗哌卡因(浓度0.375%)+200 mg硫酸镁(浓度10%),比较两组患者术后疼痛的视觉模拟评分(VAS)、吗啡使用总量、吗啡首次使用时间、不良反应情况等。结果研究组术后6、8、12 h的VAS评分皆低于对照组(P<0.05);研究组术后24 h使用的吗啡总量少于对照组,镇痛药物首次使用时间晚于对照组(P<0.05);两组术后24 h的恶心呕吐、躁动、呼吸抑制等不良反应发生率比较无统计学意义(P>0.05)。结论硫酸镁复合罗哌卡因行TAP阻滞用于腹腔镜子宫切除术术后镇痛效果理想,不会产生严重不良反应,且对止痛药的依赖更小,有助于降低阿片类药物用量,促进患者更快康复。
Objective To probe into the influence of magnesium sulfate combined with ropivacaine for transverse abdominis plane(TAP)block on postoperative analgesia after laparoscopic hysterectomy.Methods A total of 58 cases undergoing laparoscopic hysterectomy from November 2019 to November 2020 were selected and randomly divided into a control group(n=29)and a study group(n=29).The patients of the two groups underwent bilateral TAP block.The control group was injected with 20 mL ropivacaine(0.375%)+2 mL normal saline in each side,and the study group was injected with 20 mL ropivacaine(0.375%)+200 mg magnesium sulfate(10%)in each side.Then,the Visual Analogue Scale(VAS)score,total amount of morphine,time of first use of morphine,and adverse reactions were compared between the two groups.Results The VAS scores at postoperative 6 h,8 h,and 12 h in the study group were lower than those in the control group(P<0.05).The total amount of morphine used at postoperative 24 h in the study group was less than that in the control group,and the time of first use of analgesics was later(P<0.05).There was no significant difference in the incidence of nausea and vomiting,restlessness,respiratory depression,and other adverse reactions at postoperative 24 h between the two groups(P>0.05).Conclusion The effect of magnesium sulfate combined with ropivacaine for TAP block is ideal on postoperative analgesia after laparoscopic hysterectomy,because there are no serious adverse reactions,and less dependence on analgesics.It can reduce the dosage of opioids,and promote recovery of patients.
作者
佘锐璇
SHE Ruixuan(Department of Anesthesiology,Foshan Women and Children Hospital,Foshan 528000,Guangdong,China)
出处
《外科研究与新技术》
2021年第3期200-202,共3页
Surgical Research and New Technique
基金
佛山市卫生健康局医学科研课题(20200216)。
关键词
硫酸镁
罗哌卡因
腹横肌平面阻滞
子宫切除术
术后镇痛
Magnesium sulfate
Ropivacaine
Transversus abdominis plane block
Hysterectomy
Postoperative analgesia
