摘要
中医认为抗肿瘤药物所致肺毒性可根据临床表现归属中医学"咳嗽""喘证""肺胀""肺痿""肺痹"等范畴。病因与正气虚损(内因)和邪毒入侵(外因)关系密切。本病是因虚得病,因虚致实,虚以阴虚、气虚多见,实以气滞、血瘀、痰凝、毒聚为主,病位在肺,与脾、肾关系密切,是一种全身属虚,局部属实的疾病。临床辨证分型以肺脾气虚证、气阴两虚证、痰湿蕴肺证、热毒瘀结证、阳虚水泛证最为多见。文章旨在探讨抗肿瘤药物所致肺毒性的中医辨证论治思路及方法,以期为相关研究提供参考。
Pulmonary toxicity caused by antineoplastic drug can be classified into the categories of “cough” “dyspnea” “lung distension” “lung flaccidity” and “lung-Bi(肺痹)” in TCM based on clinical manifestations.Causes include deficiency of vital-Qi(正气)(internal cause) and Xiedu(邪毒) invade(external cause).This disease is caused by deficiency,and excess caused by deficiency.Deficiency is common in Yin-deficiency(阴虚) and Qi-deficiency;excess is mainly based on stagnation of Qi (气),blood stasis,phlegm coagulation,and accumulation of Du(毒).The disease is located in the lungs and is closely related to the spleen and kidneys;it is a disease that is deficient in the whole body and excess in part.The most common types of clinical syndromes are Qi-deficiency of the lung and spleen,deficiency of both Qi and Yin(阴),phlegm-damp amassing in lung,heat toxin and stasis,and water overflowing due to Yangdeficiency(阳虚).In this article,the thoughts and methods of TCM syndrome differentiation and treatment for pulmonary toxicity caused by antineoplastic drug are discussed in order to provide reference for related research.
出处
《中医临床研究》
2021年第22期62-64,共3页
Clinical Journal Of Chinese Medicine
基金
昆明市科技计划重点项目(2019-1-S-25318000001452)。
关键词
抗肿瘤药物
肺毒性
中医辨治
Antineoplastic drug
Pulmonary toxicity
TCM syndrome differentiation and treatment
