摘要
目的分析2013、2018年广东省社区高血压患者血脂异常的患病率及其相关因素。方法该研究为横断面研究。分别入选2013年1至12月和2018年1至12月广东省不同社区年度管理的社区高血压患者。由经过统一培训并考核合格的人员对入选者进行问卷调查和样本采集。主要采集入选患者的人口学信息、既往史、家族史和服用药物史等一般临床资料。血脂异常为具有下列至少1种情况,即总胆固醇(TC)水升高(≥5.2 mmol/L)、甘油三酯(TG)水平升高(≥1.7 mmol/L)、低密度脂蛋白胆固醇(LDL-C)水平升高(≥3.4 mmol/L)或高密度脂蛋白胆固醇(HDL-C)水平降低(<1.0 mmol/L)。血脂异常发生率根据2010年中国人口普查数据进行标化,并进一步行性别和年龄(<50,50~60,≥60岁)亚组分析。采用单因素和多因素logistic回归模型分析入选的高血压患者血脂异常发生的相关因素。结果在2013、2018年分别入选患者7 866例[年龄(62.4±13.6)岁,女性4 148 例(52.7%)]、11 611例[年龄(58.2±9.3)岁,女性6 692例(57.6%)]。2013年广东省社区高血压患者血脂异常的总患病率为56.3%,其中高TC血症、高TG血症、高LDL-C血症和低HDL-C血症的患病率分别为17.1%、21.3%、2.3%和24.4%;2018年广东省社区高血压患者血脂异常的总患病率为47.3%,其中高TC血症、高TG血症、高LDL-C血症和低HDL-C血症的患病率分别为14.1%、20.3%、12.0%和19.4%。性别亚组分析结果显示,2013、2018年广东省社区高血压男性患者血脂异常的总患病率为59.0%、50.7%,其中高TC血症为13.8%、8.0%,高TG血症为22.3%、20.9%,高LDL-C血症为1.7%、8.1%,低HDL-C血症为32.9%、30.3%;2013、2018年广东省社区高血压女性患者血脂异常的总患病率为53.9%、44.8%,其中高TC血症为20.5%、18.5%,高TG血症为20.4%、19.8%,高LDL-C血症为2.7%、14.9%,低HDL-C血症为16.8%、11.3%。年龄亚组分析结果显示,2013年广东省社区年龄<50、50~60和≥60岁的高血压�
Objective To analyze the prevalence trends and related factors of hypertension patients complicating with dyslipidemia in community.Methods This was a cross-sectional survey,patients with hypertension were selected from the different communities of Guangdong province in 2013 and 2018 respectively.General clinical characteristics,including demographic information,past history,family history,and medication history,were collected.Dyslipidemia was defined as follows:at least 1 item elevation of total cholesterol(TC)≥5.2 mmol/L,triglyceride(TG)≥1.7 mmol/L,low-density lipoprotein cholesterol(LDL-C)≥3.4 mmol/L,or reduced high-density lipoprotein cholesterol(HDL-C)<1.0 mmol/L.The incidence of dyslipidemia was standardized based on the 2010 China Census data,and further subgroup analysis was performed according to age(<50,50-60,≥60 years old)and sex(male,female).Multivariate logistic regression was used to analyze the related factors of dyslipidemia.Results In 2013 and 2018,7866(4148(52.7%)females,with the age of(62.4±13.6)years)and 11611(6692(57.6%)females,with the age of(58.2±9.3)years)patients with hypertension were enrolled for data analysis,respectively.In 2013,the total prevalence rate of dyslipidemia in patients with hypertension in the community of Guangdong province was 56.3%,among which the prevalence rates of hypercholesterolemia,hypertriglyceridemia,high LDL-Cemia,and low HDL-Cemia were 17.1.%,21.3%,2.3%and 24.4%,respectively.The total prevalence of dyslipidemia in patients with hypertension in the community of Guangdong in 2018 was 47.3%,prevalence of hypercholesterolemia,hypertriglyceridemia,high LDL-Cemia and low HDL-Cemia was 14.1%,20.3%,12.0%and 19.4%,respectively.Subgroup analysis showed that the total prevalence of dyslipidemia in male patients with hypertension in the community of Guangdong in 2013 and 2018 was 59.0%and 50.7%,respectively,among which hypercholesterolemia was 13.8%and 8.0%,and hypertriglyceridemia was 22.3%,20.9%,high LDL-Cemia was 1.7%,8.1%,low HDL-Cemia was 32.9%,30.3%,respe
作者
黄雨晴
李捷
陈纪言
冯颖青
Huang Yuqing;Li Jie;Chen Jiyan;Feng Yingqing(Guangdong Cardiovascular Institute,Department of Cardiology,Guangdong Provincial People′s Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,China)
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2021年第10期986-992,共7页
Chinese Journal of Cardiology
基金
中华国际医学交流基金会-中华心血管病发展专项基金-心脏健康科研基金(Z-2019-42-1908)
广东省重点领域研发计划(2019B020227005)。
关键词
高血压
血脂异常
患病率
危险因素
Hypertension
Dyslipidemias
Prevalence
Risk factors
