摘要
目的:采用基于Micro-CT三维重建的有限元分析和应变片测量相结合的方法探究轴向压缩载荷下老年和青年大鼠尺骨表面的应变分布情况。方法:选取老年(22月龄)和青年(3月龄)SPF级雄性SD大鼠,依次使用Mimics Research 19.0、Geomagic Studio 2014和SolidWorks 2019软件对大鼠右前肢的Micro-CT图像数据进行处理,建立尺骨和桡骨三维有限元模型,然后使用Abaqus 6.14-4软件进行有限元分析计算。使用课题组前期研制的小动物长骨轴向压缩应力载荷加载系统的应变测量模块对老年和青年大鼠的尺骨表面进行应变片测量,比较有限元分析和应变片测量的结果。结果:有限元分析结果显示,老年和青年大鼠应变最大处均位于尺骨远端骨干,为使尺骨表面相同位置(远端1/3处)的最大压缩应变达到3500με,分别需要对老年大鼠和青年大鼠施加约20和38 N的轴向压缩载荷。应变片测量结果显示,为使尺骨远端1/3处表面应变达到-3500με,应分别对老年和青年大鼠施加约19和35 N的轴向压缩载荷。应变片测得数据与有限元分析结果的偏差维持在10%以内,进一步证实了有限元分析的有效性和可靠性。结论:轴向压缩载荷下老年和青年大鼠尺骨表面的应变趋势一致,为在尺骨表面达到相同应变老年大鼠相比青年大鼠需施加更高的载荷强度。
Objective To combine the finite element analysis based on 3D reconstruction of Micro-CT with strain gauge measurement to explore the strain distribution on the ulna surface of aged and young adult rats under axial compression load.Methods Aged(22 months old)and young(3 months old)SPF male SD rats were selected,and the Micro-CT image data of the right forelimbs of the rats were processed in turn using Mimics Research 19.0,Geomagic Studio 2014 and SolidWorks 2019 software to build 3D finite element models of the ulnas and radiuses,then Abaqus 6.14-4 software was used to perform finite element analysis.The strain gauge measurement was performed on the ulnar surfaces of the rats using the strain measurement module of the self-developed axial compression stress load system for animal long bone to compare the results of the finite element analysis and the strain gauge measurement.Results Finite element analysis showed that the maximum strain was located at the distal ulnar diaphysis in both the aged and young rats.To achieve the same 3500μεcompression strain at the same location on the ulnar surface(distal one third),an axial compression load of approximately 20 and 38 N should be applied to the aged and young rats respectively.Strain gage measurement found that to achieve a surface strain of-3500μεat the distal one third of the ulna,an axial compressive load of approximately 19 and 35 N should be applied to the aged and young rats respectively.The deviation between the results by strain gage measurement and finite element analysis was maintained within 10%,further confirming the validity and reliability of finite element analysis.Conclusion The strains on the ulnar surfaces of the aged and young rats under axial compression load follow the same trend,and a high load intensity is required to achieve the same strain on the ulnar surface in the aged rat compared to the young rat.
作者
杨永青
刘曦雨
颜泽栋
谭芷芬
罗二平
景达
YANG Yong-qing;LIU Xi-yu;YAN Ze-dong;TAN Zhi-fen;LUO Er-ping;JING Da(School of Biomedical Engineering,Air Force Medical University,Xi'an 710032,China)
出处
《医疗卫生装备》
CAS
2021年第11期27-31,共5页
Chinese Medical Equipment Journal
基金
国家自然科学基金面上项目(51777211,11972366)
军事科技领域青年人才托举工程项目(17-JCJQ-QT-038)。
关键词
轴向压缩载荷
尺骨
应变分布
有限元分析
应变片测量
axial compression load
ulna
strain distribution
finite element analysis
strain gauge measurement
