摘要
目的探讨膀胱内药物膀胱灌注联合心理护理在间质性膀胱炎/膀胱疼痛综合征(IC/BPS)患者治疗中的疗效,以指导临床治疗。方法2015年11月至2019年5月,泌尿外科共收治IC/BPS患者71例。其中女61例,男10例。年龄21~76岁,平均(43±11)岁。病程6~242个月,平均(63±21)个月。IC/BPS患者症状评估采用O'Leary-Sant调查表和盆腔疼痛和尿频尿急症状评分表(PUF评分表),IC/BPS患者焦虑评估采用焦虑自评量表(SAS),抑郁评估采用贝克抑郁量表(BDI-Ⅱ)。所有患者均行麻醉下膀胱镜检查及水扩张。对水扩张后所有患者均行膀胱内透明质酸钠灌注,根据是否进行心理护理及指导分为两组,比较两组治疗前及治疗后(1个月、3个月、6个月)的疗效情况。结果与治疗前相比,两组患者治疗后第1、3、6个月时的各项观察指标均得以改善(P<0.05)。治疗1个月后各项观察指标两组间比较差异无统计学意义(P>0.05);但治疗后3个月与治疗后6个月,各项观察指标两组间比较差异均具有统计学意义(P<0.05)。结论膀胱内透明质酸钠灌注可有效缓解IC/BPS患者的症状,而在长期疗效中膀胱内药物灌注联合心理护理优于单纯进行膀胱内药物灌注。
Objective To explore the curative effect of intravesical drug intravesical instillation combined with psychological nursing in the treatment of interstitial cystitis/bladder pain symptom(IC/BPS)patients and guide the clinical treatment.Methods From November 2015 to may 2019,71 patients with IC/BPS were admitted.There were 61 women and 10 men.The average age was(43±11)years.The course of disease ranged from 6 to 242 months,with an average of(63±21)months.The symptoms of IC/BPS were assessed by O'Leary Sant questionnaire,pelvic pain and frequency of urination and urgency of urination symptom scale(PUF scale),the anxiety of IC/BPS patients was assessed by Self-rating Anxiety Scale(SAS),and the depression was assessed by Beck Depression Scale(BDI-Ⅱ).All patients underwent cystoscopy and hydrodilation under anesthesia.After water dilation,all patients were perfused with sodium hyaluronate in bladder.According to whether psychological care and guidance were carried out,they were divided into two groups.The curative effect of the two groups before and after treatment(1 month,3 months,6 months)was compared.Results Compared with before treatment,all the observation indexes of the two groups were improved at the 1st,3rd and 6th month after treatment(P<0.05).There was no significant difference between the two groups(P>0.05)1 month after treatment,and there was significant difference between the two groups 3 months and 6 months after treatment(P<0.05).Conclusion Intravesical sodium hyaluronate infusion can effectively relieve the symptoms of IC/BPS patients,and in the long-term effect,intravesical drug infusion combined with psychological nursing is better than intravesical drug infusion alone.
作者
谢文君
李文标
周颖
罗慧
Xie Wenjun;Li Wenbiao;Zhou Yin;Luo Hui(Department of Surgical Anesthesia Center,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Urology,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China)
出处
《中华腔镜泌尿外科杂志（电子版）》
2021年第5期436-439,共4页
Chinese Journal of Endourology(Electronic Edition)
基金
广东省医学科学技术研究基金项目(A2019560)。
关键词
间质性膀胱炎
膀胱灌注
心理护理
Interstitial cystitis
Intravesical therapy
Psychosocial nursing
