摘要
埃马纽埃尔·卡彭蒂耶和珍妮弗·杜德纳,因合作开发基因编辑技术——CRISPR/Cas9“基因剪刀”而获得2020年诺贝尔化学奖。CRISPR/Cas9技术的低成本、强易用性和高效率,促进了生命科学的突破性发展,也使它拥有了巨大的商业价值。通过回顾两位科学家的科研历程和基因编辑领域的成就,提出了相关的思考和启示。
Emmanuelle Marie Charpentier and Jennifer Anne Doudna were awarded the Nobel Prize in Chemistry 2020.The CRISPR/Cas9 gene editing technology,the"gene scissors",was jointly developed by the two female scientists.Due to its low cost and high ease,the CRISPR/Cas9 technology greatly promotes the development of the life sciences.The huge commercial value of this technology is also recognized by the society.This paper reviews the scientific researches of the two scientists,as well as the impact and the enlightenment of their results.
作者
陈彪
付小航
朱玥玮
狄雨萌
吴又进
CHEN Biao;FU Xiaohang;ZHU Yuewei;DI Yumeng;WU Youjin(Department of History of Science and Scientific Archaeology,University of Science and Technology of China,Hefei 230026,China)
出处
《科技导报》
CAS
CSCD
北大核心
2021年第20期142-148,共7页
Science & Technology Review
基金
安徽省高等学校省级质量工程项目(2019jyxm0014,2014jyxm015)
中国科学技术大学校级教学研究项目(2018jyy13,2021ycjg12,2020kcsz062)。