摘要
目的观察针刺联合中药熏蒸疗法治疗军事训练所致急性膝关节创伤性滑膜炎(TSKJ)的疗效及对关节液中炎症因子和脂肪因子的影响。方法将83例急性TSKJ患者按照分层随机法分为3组,均予常规治疗。对照组27例加用双氯芬酸钠肠溶片口服治疗,针刺组28例加用针刺治疗,针刺联合中药组28例加用针刺联合中药熏蒸疗法。3组均治疗2周。比较3组疗效;观察3组治疗前后西安大略和麦克马斯特大学(WOMAC)骨关节炎指数评分变化;观察3组治疗前后关节液中炎症因子、脂肪因子含量变化。结果对照组总有效率70.37%(19/27),针刺组总有效率92.86%(26/28),针刺联合中药组总有效率96.43%(27/28),针刺组、针刺联合中药组疗效优于对照组(P<0.05),针刺联合中药组疗效优于针刺组(P<0.05)。3组治疗后疼痛、僵硬、活动功能评分及总评分均较本组治疗前降低(P<0.05),且针刺组、针刺联合中药组疼痛、僵硬、活动功能评分及总评分均低于对照组(P<0.05),针刺联合中药组低于针刺组(P<0.05)。3组治疗后关节液中超敏C反应蛋白(hs-CRP)、白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)含量均低于本组治疗前(P<0.05),且针刺组、针刺联合中药组关节液中hs-CRP、IL-6、TNF-α含量均低于对照组(P<0.05),针刺联合中药组低于针刺组(P<0.05)。3组治疗后关节液中瘦素、抵抗素、内脂素、趋化素含量均较本组治疗前降低(P<0.05),且针刺组、针刺联合中药组关节液中瘦素、抵抗素、内脂素、趋化素含量均低于对照组(P<0.05),针刺联合中药组低于针刺组(P<0.05)。结论针刺联合中药熏蒸疗法治疗急性TSKJ,有助于改善患者膝关节功能,提高临床疗效,可能与降低关节液中炎症因子、脂肪因子含量有关。
Objective To observe the clinical effect of acupuncture combined with traditional Chinese medicine(TCM)thermal fog therapy for acute traumatic synovitis of knee joint(TSKJ)due to military training and its effect on inflammatory factors and adipocytokines in acute traumatic knee effusions(ATE).Methods Totally 83 patients with acute TSKJ were divided into control group(n=27),acupuncture group(n=28),combined group(n=28)in stratified random sampling.Except for conventional treatment,patients in control group were given with oral diclofenac sodium enteric-coated tablets,acupuncture group with acupuncture theraphy,and combined group with acupuncture combined with TCM thermal fog therapy.The treatment continued 2 weeks to compare Western Ontario and McMaster Universities(WOMAC)osteoarthritis index,and inflammatory factors and adipocytokines in ATE and the curative effect between groups.Results The total effective rates were 70.37%(19/27),92.86%(26/28),96.43%(27/28)in control group,acupuncture group,combined group,respectively;acupuncture group were better than control group and combined group were better than acupuncture group(all P<0.05).After treatment,WOMAC osteoarthritis index(pain,stiffness,and motor function)in groups were decreased(P<0.05),which in the comparison of the three,combined group and acupuncture group decreased notably in compared with control group,combined group decreased markedly acupuncture group(P<0.05).inflammatory factors such as high-sensitivity c-reactive protein(hs-CRP),interleukin 6(IL-6),tumor necrosis factor-alpha(TNF-α)of ATE in groups remarkably decreased(P<0.05),combined group is the lowest among groups,the order of arrangement in turn:combined group,acupuncture group,control group(all P<0.05).Adipocytokines(leptin,resistin,visfatin,chemotaxins)of ATE in groups were lower(P<0.05),among three groups,acupuncture group were lower than control group(P<0.05),and combined group were lower than acupuncture group(P<0.05).Conclusion For patients with acute TSKJ,the combined therapy can improve
作者
谢博多
文学
张红文
张志强
王晓辉
穆森
张利泰
XIE Boduo;WEN Xue;ZHANG Hongwen;ZHANG Zhiqiang;WANG Xiaohui;MU Sen;ZHANG Litai(Department of TCM Rehabilitation,The 981 Hospital of the Joint Logistic Support Force of PLA,Chengde,Hebei 067000;不详)
出处
《河北中医》
2021年第7期1165-1169,1173,共6页
Hebei Journal of Traditional Chinese Medicine
基金
2018年度全军保健专项课题(编号:18BJZ19)。
关键词
滑膜炎
膝关节
针刺疗法
Synovitis
Knee joint
Acupuncture therapy
