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老年慢性支气管炎应用不同药物雾化吸入的临床效果观察 被引量:1

Clinical effect of atomization inhalation with different drugs in elderly patients with chronic bronchitis
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摘要 目的分析对老年慢性支气管炎患者应用不同药物雾化吸入的临床效果。方法100例老年慢性支气管炎患者随机分为观察组与对照组,每组50例。所有患者均接受布地奈德雾化吸入治疗,观察组加用沐舒坦治疗。比较两组治疗效果、症状缓解时间及住院时间、治疗期间痰量、安全性。结果观察组治疗总有效率为98.00%,高于对照组的82.00%,差异有统计学意义(P<0.05)。观察组患者胸闷、咳嗽、哮喘缓解时间以及住院时间分别为(2.87±0.27)、(2.90±0.30)、(2.92±0.32)、(5.88±0.55)d,均短于对照组的(3.65±0.34)、(4.01±0.40)、(4.12±0.41)、(7.98±0.65)d,差异有统计学意义(P<0.05)。观察组患者治疗第1天、第2天、第3天的痰量高于对照组,差异有统计学意义(P<0.05);治疗第4天,两组痰量比较差异无统计学意义(P>0.05);观察组患者治疗第5天的痰量低于对照组,差异有统计学意义(P<0.05)。两组患者治疗期间均未发生不良反应。结论对老年慢性支气管炎患者应用布地奈德+沐舒坦雾化吸入治疗,可有效缩短各临床症状改善情况,痰量得以有效减少,临床效果显著,治疗安全性较高,有较高的临床应用价值。 Objective To analyze the clinical effect of atomization inhalation with different drugs in elderly patients with chronic bronchitis.Methods A total of 100 elderly patients with chronic bronchitis were randomly divided into observation group and control group,with 50 cases in each group.All patients were treated with budesonide atomization inhalation,and the observation group was treated with mucosolvan.Both groups were compared in terms of therapeutic effect,symptom remission time,hospitalization time,sputum volume and safety.Results The total effective rate of treatment in the observation group was 98.00%,which was higher than 82.00%in the control group,and the difference was statistically significant(P<0.05).The remission time of chest tightness,cough,asthma and hospitalization time of the observation group were(2.87±0.27),(2.90±0.30),(2.92±0.32),(5.88±0.55)d,which were shorter than(3.65±0.34),(4.01±0.40),(4.12±0.41),(7.98±0.65)d of the control group,and the differences were statistically significant(P<0.05).The sputum volume of the observation group on the 1st,2nd and 3rd day of treatment was higher than that of the control group,and the difference was statistically significant(P<0.05).On the 4th day of treatment,there was no statistically significant difference in sputum volume of between the two groups(P>0.05).On the 5th day of treatment,the sputum volume in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).No adverse reactions occurred during treatment in both groups.Conclusion Atomization inhalation with budesonide and mucosolvan has significant clinical effect on elderly patients with chronic bronchitis,and it can effectively shorten the improvement of clinical symptoms,reduce the sputum volume,with high safety,which contains high clinical application value.
作者 潘微微 PAN Wei-wei(Department of Respiratory Pneumoconiosis,Huludao Central Hospital Chemical Branch,Huludao 125000,China)
出处 《中国现代药物应用》 2021年第19期127-129,共3页 Chinese Journal of Modern Drug Application
关键词 慢性支气管炎 布地奈德 沐舒坦 雾化吸入 临床效果 Chronic bronchitis Budesonide Mucosolvan Atomization inhalation Clinical effect
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