摘要
酰胺质子转移成像是一种新型磁共振分子成像技术。它是化学交换饱和转移成像的一个分支,通过检测组织内源性蛋白质或多肽中的酰胺质子-水质子交换速率反映细胞内蛋白质浓度及pH值变化。本文拟对酰胺质子转移成像在泌尿生殖系统疾病中的应用进展做一综述。
Amide proton transfer(APT)imaging is a new magnetic resonance molecular imaging technique.It is a branch of chemical exchange saturation transfer imaging,which reflects the changes of intracellular protein concentration and pH value by detecting the proton-water exchange rate of amide protons in tissues.In this paper,the applications of APT imaging in genitourinary diseases are reviewed.
作者
孔雅晴
曲倩倩
明蕾
王哲
邓凯
KONG Yaqing;QU Qianqian;MING Lei;WANG Zhe;DENG Kai(Shandong First Medical University(Shandong Academy of Medical Sciences),Jinan 271016,China;Department of Radiology,the first affiliated Hospital of Shandong First Medical University(Shandong QianFoshan Hospital),Jinan 250014,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2021年第10期118-120,共3页
Chinese Journal of Magnetic Resonance Imaging
关键词
酰胺质子转移成像
磁共振成像
前列腺癌
子宫内膜癌
子宫颈癌
amide proton transfer imaging
magnetic resonance imaging
prostate cancer
endometrial cancer
cervical cancer