摘要
目的探讨类风湿关节炎患者伴焦虑、抑郁状态的分布情况及其与中医证型的相关性。方法选取2019年3月—2021年3月期间陕西省人民医院中医科收治的108例类风湿关节炎患者为研究对象,观察并分析患者焦虑、抑郁情况及其中医证候分布情况及类风湿关节炎与中医证型的相关性。结果108例类风湿关节炎患者中单纯类风湿关节炎占比最高,为55.56%(60/108),其次为合并焦虑、抑郁20.37%(22/108),单纯抑郁12.96%(14/108)及单纯焦虑11.11%(12/108)。单纯类风湿关节炎患者及合并焦虑、抑郁患者以痰瘀痹阻证最为常见,分别为21.67%(13/60)、22.73%(5/22),单纯焦虑患者以痰瘀痹阻证最为常见25.00%(3/12),单纯抑郁患者以寒湿痹阻证和瘀血阻络证最为常见,均为21.43%(3/14)。单纯类风湿关节炎、合并焦虑抑郁与痰瘀痹阻证呈正相关,单纯焦虑与痰瘀痹阻证、寒湿痹阻证呈正相关,单纯抑郁与寒湿痹阻证、瘀血阻络证呈正相关,差异均有统计学意义(P<0.05)。结论在类风湿关节炎患者中合并焦虑、抑郁的发生率较高,中医证型以痰瘀痹阻证最为常见。
Objective This study aims to explore the distribution of anxiety and depression in patients with rheumatoid arthritis and its correlation with TCM syndrome types.Methods 108 patients with rheumatoid arthritis admitted to the Department of Traditional Chinese Medicine of Shaanxi Provincial People′s Hospital from March 2019 to March 2021 were used as the research objects to observe their anxiety,depression,the distribution of TCM syndromes,and the relationship between rheumatoid arthritis and rheumatoid arthritis.Results Among the 108 patients with rheumatoid arthritis,simple rheumatoid arthritis accounted for the highest proportion was 55.56%(60/108),followed by combined anxiety,depression 20.37%(22/108),simple depression 12.96%(14/108)and simple anxiety 11.11%(12/108).The syndrome of phlegm and blood stasis is the most common in patients with simple rheumatoid arthritis and those with anxiety and depression were 21.67%(13/60)and 22.73%(5/22).The syndrome of phlegm and stasis is the most common in patients with simple anxiety 25.00%(3/12).Patients with simple depression have the syndrome of cold-dampness obstruction syndrome and blood stasis obstructing collaterals syndrome are the most common,both are 21.43%(3/14).Simple rheumatoid arthritis,combined with anxiety and depression are positively correlated with phlegm-stasis-blocking syndrome,simple anxiety is positively related with phlegm-stasis-blocking syndrome,cold-dampness blocking syndrome,and simple depression is positive with cold-dampness blocking syndrome and blood stasis blocking collaterals syndrome.Correlation,differences were statistically significant(P<0.05).Conclusion The incidence of anxiety and depression is relatively high in patients with rheumatoid arthritis,and the most common TCM syndrome is the syndrome of phlegm and blood stasis and obstruction.
作者
姜小帆
曹雯
陈芳
李娟娥
JIANG Xiao-fan;CAO Wen;CHEN Fang;LI Juan-e(Department of Traditional Chinese Medicine,Shaanxi Provincial People′s Hospital,Xi′an Shaanxi 710068;Department of Nephrology,Xi′an Hospital of Traditional Chinese Medicine,Xi′an Shaanxi 710016;Shaanxi Institute of Food and Drug Administration,Xi′an Shaanxi 710065)
出处
《世界中西医结合杂志》
2021年第9期1569-1572,共4页
World Journal of Integrated Traditional and Western Medicine
基金
陕西省科学技术研究发展计划项目(2020KJ1303)。
关键词
类风湿关节炎
焦虑
抑郁
中医证型
相关性
Rheumatoid Arthritis
Anxiety
Depression
TCM Syndrome
Correlation