摘要
目的:探讨氯雷他定联合布地奈德雾化治疗对支气管哮喘患儿炎症因子水平的影响。方法:选取2020年4月~2021年4月某院收治的支气管哮喘患儿72例进行研究,随机分为对照组和研究组各36例,对照组采用布地奈德雾化治疗,研究组采用氯雷他定联合布地奈德雾化治疗,比较两组患者治疗前后的炎症因子水平和治疗效果。结果:治疗后,研究组IL-6、TNF-α指标优于对照组(P<0.05);研究组总有效治疗率明显高于对照组(P<0.05)。结论:在儿童支气管哮喘的临床治疗中,氯雷他定联合布地奈德雾化剂疗效更佳,可显著改善儿童炎症因子水平。
Objective:To investigate the effect of loratadine combined with budesonide atomization on the levels of inflammatory factors in children with bronchial asthma.Methods:72 children with bronchial asthma admitted to a hospital from April 2020 to April 2021 were selected for this study,and randomly divided into control group(n=36 cases)and study group(n=36 cases).The control group was treated with budesonide atomization,and the study group was treated with loratadine combined with budesonide atomization.The levels of inflammatory factors before and after treatment and the treatment effect were compared between the two groups.Results:After treatment,the indexes of IL-6 and TNF-αin study group were better than those in control group(P<0.05).The total effective treatment rate of study group was significantly higher than that of control group(P<0.05).Conclusion:In the clinical treatment of children with bronchial asthma,loratadine combined with budesonide atomizer is more effective and can significantly improve the level of inflammatory factors in children.
作者
郭继伟
Guo Jiwei(Department of Pediatrics,Taikang County People's Hospital,Zhoukou 461400)
出处
《数理医药学杂志》
CAS
2021年第10期1529-1530,共2页
Journal of Mathematical Medicine
关键词
氯雷他定
布地奈德
雾化
支气管哮喘
炎性因子
loratadine
budesonide
atomization
bronchial asthma
inflammatory factors
