摘要
随着规模化养殖业发展,不合理甚至违法添加使用兽用抗生素导致的药物残留,严重威胁着动物源性食品安全,迫切需要建立灵敏可靠的残留分析方法,而检测方法成功的关键是从复杂的生物样品中准确提取纯化微量的残留药物。分子印迹技术具有特异性强、灵敏度高、操作简便等优点,在兽药残留检测中得到越来越多重视。主要综述了分子印迹聚合物的最新制备方法及其在兽用抗生素残留分析中的最新应用进展。
With the development of large-scale breeding industry,drug residues caused by unreasonable or even illegal addition of veterinary antibiotics have become an important factor threatening the safety of animal derived food.It is urgent to establish a sensitive and reliable method for the analysis of veterinary drug residues.The key to the success of the detection method is to accurately extract and purify trace residual drugs from complex biological samples.Molecular imprinting technology has the advantages of strong specificity,high sensitivity and simple operation,which has been paid more and more attention in the detection of veterinary drug residues.In this paper,the latest preparation methods of molecularly imprinted polymers and the latest research progress in veterinary antibiotic residue detection were reviewed.
作者
王晓通
张晓彤
谢晓程
玄艺
李建科
成子强
李臣贵
WANG Xiao-tong;ZHANG Xiao-tong;XIE Xiao-cheng;XUAN Yi;LI Jian-ke;CHENG Zi-qiang;LI Chen-gui(School of Animal Science and Technology, Shandong Agricultural University, Tai' an, Shandong 271018,China;Key Laboratory of Animal Bioengineering and Disease Control in Shandong Province, Tai' an, Shandong 271018,China)
出处
《中国兽药杂志》
2021年第9期50-56,共7页
Chinese Journal of Veterinary Drug
基金
国家自然科学基金(31602111)
山东省重大科技创新工程(2019 JZZY010735)。
关键词
兽用抗生素
残留
分子印迹
检测
veterinary antibiotics
residue
molecular imprinting
detection