摘要
以香草醛为模板分子,二氧化硅为载体,α-甲基丙烯酸为功能单体,乙二醇二甲基丙烯酸酯为交联剂合成了香草醛分子印迹聚合物(VanMIP)。以此为识别元件,结合Luminol-K_(3)Fe(CN)_(6)化学发光体系制成传感器,对香草醛进行检测。在优化条件下,香草醛浓度在0.4~14 nmol/L范围内与化学发光强度具有良好的线性关系,相关系数为0.9989,检出限(LOD)低至0.16 nmol/L。对6.0 nmol/L的香草醛溶液连续测定11次,其相对标准偏差(RSD)为0.9%。通过对化学发光光谱、紫外-可见吸收光谱和电子自旋光谱的研究,提出了化学发光的可能机理。
A molecularly imprinted polymer for vanillin was synthesized by the molecular imprinting technique using vanillin as template molecule,silica as carrier,α-methacrylic acid as functional monomer and ethylene glycol dimethacrylate as crosslinker.The synthetic polymer was used as the recognition element and combined with Luminol-K_(3)Fe(CN)_(6) chemiluminescence system to make a sensor for the determination of vanillin.Under the optimal experimental conditions,there was a good linear relationship between relative intensity of chemiluminescence and vanillin in the concentration range of 0.4-14 nmol/L,and the correlation coefficient was0.9989,with limit of detection(LOD)of 0.16 nmol/L.The relative standard deviation(RSD)of 6.0 nmol/L vanillin solution was measured to be 0.9%for 11 times.The possible mechanism of chemiluminescence is proposed through the study of chemiluminescence spectra,UV-Vis absorption spectra and electron spin spectra.
作者
李青轻
陈磊
蒲婷
张贵
杨春艳
LI Qingqing;CHEN Lei;PU Ting;ZHANG Gui;YANG Chunyan(Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province,College of Chemistry and Chemical Engineering,China West Normal University,Nanchong 637002)
出处
《分析试验室》
CAS
CSCD
北大核心
2021年第9期1065-1069,共5页
Chinese Journal of Analysis Laboratory
基金
四川省化学合成与污染控制重点实验室开放项目(11CSPC-(1-7))
四川省教育厅重点项目(15ZA0153)
西华师范大学英才科研基金项目(17YC036)资助。
关键词
香草醛
分子印迹聚合物
流动注射-化学发光
奶糖
vanillin
molecularly imprinted polymers
flow injection-chemiluminescence(FI-CL)
milk sugar
