摘要
邻苯二甲酸酯(PAEs)是工业中常用的塑化剂和溶剂,人体主要通过饮食摄入、皮肤接触和空气吸入三大途径暴露吸收。人体生物样本尿、血、唾液、精液和母乳等普遍含有PAEs及其代谢产物,不同PAEs代谢产物在不同生物样本中的浓度不同。普通人群中儿童PAEs暴露水平高于成人,女性PAEs暴露水平高于男性;职业人群PAEs暴露水平高于普通人群。本文对国内外普通人群及职业暴露人群的PAEs相关人体生物监测研究作综述,为减少PAEs暴露、降低相关健康风险提供依据。
Phthalic acid esters(PAEs) are commonly used plasticizers and solvents. Human body is exposed and absorbed mainly through diet, skin and air inhalation. The biological samples such as urine, blood, saliva, semen and breast milk generally contain PAEs and their metabolites, but the concentrations of PAEs metabolites vary in different samples. In the general population, the levels of PAEs are higher in children than in adults, and higher in women than in men;the levels of PAEs are higher in the occupational population than in the general population. In this paper, the research of PAEs related human biomonitoring in the general population and occupational population at home and abroad is reviewed, so as to provide the basis for reducing the exposure of PAEs and related health risk.
作者
刘静
徐沛维
陈志健
邵斌
施长苗
李胜
王晓峰
LIU Jing;XU Peiwei;CHEN Zhijian;SHAO Bin;SHI Changmiao;LI Sheng;WANG Xiaofeng(Department of Health Surveillance,Changxing Center for Disease Control and Prevention,Changxing,Zhejiang 313100,China)
出处
《预防医学》
2021年第9期906-909,912,共5页
CHINA PREVENTIVE MEDICINE JOURNAL
关键词
邻苯二甲酸酯
生物监测
暴露水平
职业暴露
phthalic acid esters
biomonitoring
exposure level
occupational exposure