摘要
Mesenchymal stromal cells(MSCs)and macrophages are normal components of the bone marrow micro-environment and important regulators of normal hematopoiesis.1 Consequently,MSC and macrophage dysfunctions are associated with an abnormal bone marrow micro-environment and abnormal hematopoiesis.In some circumstances,these abnormalities support the growth of leukemia cells but how this occurs is unknown.Also unknown is whether there is an important interaction between these cell types.
基金
I acknowledge support from the National Institute of Health Research(NIHR)Biomedical Research Centre funding scheme.
