摘要
Astrocyte,one of the most abundant glial cell types,actively functions in stabilizing neural circuits and synaptic transmission in the central nervous system(CNS).Astrocytes not only provide metabolic and trophic supports to various CNS neurons and but also actively work in assisting synaptic transmission and plasticity.A line of growing evidences have documented that astrocytes present as an essential coordinatorin neural circuit function.[1]Firstly,calcium signaling or calcium wave calcium(Ca^(2+))between neighboring astrocytes contribute to establishment of a huge astrocytic glial network by gap-junctions,which has updated the understanding of astrocyte function in CNS,and led to an idea that astrocytes are powerful regulators of neuronal spiking.
基金
Supported by grants from the National Natural Science Foundation of China(31371374)
the National Basic Research Program(2012CB525002).
