摘要
对肠道微生物和心血管疾病相关的文献进行计量聚类共现分析和系统性分析,概述研究现况。相关研究10多年前涌现,近年激增且趋势不减。TMO和SFCAs对心血管疾病的重要性远超以往的认识,益生菌和微生物生态治疗也呼之欲出。代谢综合征(肥胖、糖尿病)和高血压、动脉粥样硬化等心血管疾病的发生与肠菌关系密切,机制和影响途径日渐清晰。深入且多方面理解肠道微生物和心血管疾病的关系,对防治和康复均有重要意义,但目前厘清两者之间确切的因果关系尚需更多、更细致的研究。
This paper analyzes the literature related to intestinal microbiome and cardiovascular diseases by quantitative cluster co-occurrence analysis and systematic analysis,and summarizes the research status.Related studies emerged more than 10 years ago,and have proliferated in recent years.The importance of TMO and SFCAs for cardiovascular disease is far greater than previously recognized,and probiotics and microbial ecological therapies are also emerging.The occurrence of metabolic syndrome(obesity,diabetes),hypertension,atherosclerosis and other cardiovascular diseases is closely related to intestinal bacteria,and the mechanism and influencing pathways are becoming increasingly clear.In-depth and comprehensive understanding of the relationship between intestinal microbiome and cardiovascular disease is of great significance for prevention and treatment and rehabilitation,but more and more detailed studies are needed to clarify the exact causal relationship between the two.
作者
高标
王施(综述)
李红霞
沈慧(审校)
GAO Biao;WANG Shi;LI Hong-xia;SHENG Hui(Support Center of Teaching and Research,Naval Medical University,Faculty of Naval Medicine,Naval Medical University,Shanghai 200433,China;Department of Neurology,Third Affiliated Hospital of Naval Medical University,3 Faculty of Naval Medicine,Naval Medical University,Shanghai 200433,China;Department of Nutrition and Food Hygiene,Faculty of Naval Medicine,Naval Medical University,Shanghai 200433,China)
出处
《医学研究生学报》
北大核心
2021年第9期979-984,共6页
Journal of Medical Postgraduates
基金
国家自然科学基金(81573150)
上海市卫生与计划生育委员会科研课题(201840360)。
关键词
肠道微生物
心血管疾病
现况
intestinal microbes
cardiovascular disease
status guo
