摘要
目的探讨硫酸镁联合硝苯地平治疗妊娠高血压综合征患者的临床疗效。方法选取本院2018年3月至2019年3月收治的妊高症患者80例,随机分为对照组(单用硫酸镁治疗)和观察组(硫酸镁联合硝苯地平治疗),各40例。比较两组临床效果、治疗前后血压水平、24 h尿蛋白定量及不良反应情况。结果治疗后,观察组治疗总有效率为95.0%,高于对照组的72.5%,差异有统计学意义(P<0.05)。治疗前,两组舒张压、收缩压以及24 h尿蛋白定量比较差异无统计学意义;治疗后,观察组舒张压、收缩压及24 h尿蛋白定量均低于对照组(P<0.05)。观察组不良反应发生率低于对照组(P<0.05)。结论硫酸镁联合硝苯地平治疗妊娠高血压综合征患者,可改善患者血压和24 h尿蛋白定量,且安全性较高,值得临床推广运用。
Objective To investigate the clinical efficacy of magnesium sulfate combined with nifedipine in the treatment of pregnancy-induced hypertension syndrome.Methods FromMarch 2018 toMarch 2019,80 patients with pregnant hypertension were selected and randomly divided into control group(magnesium sulfate alone treatment)and observation group(magnesium sulfate combined with nifedipine treatment),with 40 cases in each group.The clinical effect,blood pressure level before and after treatment,24 h urinary protein quantification and adverse reactions were compared between the two groups.Results After treatment,the total effective rate of the observation group was 95.0%,which was higher than that of the control group(72.5%),and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in diastolic blood pressure,systolic blood pressure and 24 h urinary protein between two groups.After treatment,diastolic blood pressure,systolic blood pressure and 24 h urinary protein in the observation group were lower than those in the control group(P<0.05).The incidence of adverse reactions in observation group was lower than that in control group(P<0.05).Conclusion Magnesium sulfate combined with nifedipine in the treatment of pregnancy-induced hypertension syndrome can improve the blood pressure and 24 h urinary protein quantitative,with high safety,and is worthy of clinical application.
作者
高华
GAO Hua(Department of Obstetrics and Gynecology,Songzi City People's Hospital,Jingzhou,Hubei,434200,China)
出处
《当代医学》
2021年第29期93-95,共3页
Contemporary Medicine
关键词
妊娠高血压综合征
硫酸镁
硝苯地平
舒张压
收缩压
24
h尿蛋白定量
Pregnancy-induced hypertension syndrome
Magnesium sulfate
Nifedipine
Diastolic blood pressure
Systolic blood pressure
24 h urine protein quantification
