摘要
目的研究创伤严重程度评分(injury severe score,ISS)对多发创伤患者住院期间下肢深静脉血栓形成(deep venous thrombosis,DVT)的预测价值。方法选取中国医科大学附属第一医院创伤中心2020年1月1日至2021年2月28日收治的148例多发创伤患者作为研究对象,收集其临床资料。依据超声检查结果将其分为DVT组及无DVT组,并计算DVT的发生率。采用单因素分析和多因素logistic回归分析可能影响患者DVT发生率的人口学特征、创伤严重程度及血液学指标,利用受试者工作特征曲线分析ISS评分对多发创伤患者DVT形成的预测价值。结果在148例多发创伤患者中,28例(18.92%)患者出现DVT。单因素分析显示两组ISS评分、血浆凝血酶原时间(PT)、血浆D二聚体(D-D)差异有统计学意义。多因素logistic回归分析显示ISS评分升高能够显著增加DVT的发病风险(OR=3.60;95%CI:1.33~9.71,P=0.012)。ROC显示ISS评分预测DVT形成的AUC为0.723,其敏感性为0.714,特异性为0.725。结论ISS评分是多发创伤患者DVT形成的独立危险因素,ISS评分对多发创伤患者DVT的形成具有预测价值。
Objective To study the value of injury severity score in predicting the formation of lower extremity deep vein thrombosis during hospitalization in patients with multiple trauma.Methods A total of 148 patients with multiple trauma treated in the Trauma Center of the First Hospital of China Medical University from January 1,2020 to February 28,2021 were selected as subjects,and their clinical data were collected.According to the results of ultrasound examination,they were divided into DVT group and non-DVT group,and the incidence of DVT was calculated.Univariate analysis andmultivariate logistics regression analysis were used to explore the correlation among demographic characteristics,trauma severity and hematological indexes that may affect the incidence of DVT.Receiver operating characteristic curve was used to analyze the predictive value of ISS for the formation of DVT in patients with multiple trauma.Results In 148 patients with multiple trauma,28(19.92%)developed DVT.Univariate analysis showed that there were significant differences in ultrasound severity score(injury severity score,ISS),prothrombin time(PT)and D-dimer(D-D)between the two groups.Multivariate logistics regression analysis showed that elevated ISS scores were able to significantly increase the risk of developing DVT(OR=3.60;95%CI:1.33~9.71,P=0.012).ROC showed that the AUC of DVT formation predicted by ISS was 0.723,thesensitivity was 0.714,and specificity was 0.725.Conclusion ISS is an independent risk factor for DVT formation in polytrauma patients.ISS has predictive value for the formation of DVT in patients with multiple trauma.
作者
杨超
张旭
李潭
孙树
YANG Chao;ZHANG Xu;LI Tan;SUN Shu(Trauma Center and Department of Burns,the First Hospital of China Medical University,Shenyang 110001,China;不详)
出处
《实用医学杂志》
CAS
北大核心
2021年第18期2371-2374,共4页
The Journal of Practical Medicine
基金
辽宁省自然科学基金项目(编号:2020-BS-102)。
