摘要
文章探讨了多层螺旋CT(MSCT)三维重建联合血清神经元特异性烯醇化酶(NSE)和鳞癌相关抗原(SCC-Ag)诊断肺恶性小结节的价值。选取术后病理确诊的113例恶性肺结节患者作为恶性组、100例良性肺结节患者作为良性组,对比两组患者的MSCT三维重建特征、血清NSE和SCC-Ag水平,并计算3种方式单独或联合应用诊断恶性肺小结节的价值。结果显示,恶性组的结节分叶状、外缘毛刺、胸膜凹陷、血管集束征检出率高于良性组患者(P<0.05);恶性组的血清NSE和SCC-Ag水平高于良性组患者(P<0.05);血清NSE、SCC-Ag、MSCT三维重建联合应用鉴别诊断肺良恶性结节的灵敏度为95.58%、特异度为86.00%。说明MSCT三维重建特征、血清NSE和SCC-Ag三者联合应用对诊断鉴别肺小结节具有较高的灵敏度和特异度。
This article discusses the value of multi-slice spiral CT(MSCT)three-dimensional reconstruction combined with serum neuron specific enolase(NSE)and squamous cancinoma-associated antigen(SCC-Ag)in the diagnosis of lung malignant nodules.A total of 113 patients with malignant pulmonary nodules diagnosed pathologically after surgery were selected as the malignant group,and 100 patients with benign pulmonary nodules were selected as the benign group.The MSCT three-dimensional reconstruction characteristics,serum NSE and SCC-Ag levels of the two groups were compared,and three were calculated.The value of the method alone or in combination in the diagnosis of malignant pulmonary nodules.The results showed that the detection rate of nodule lobules,outer edge burr,pleural depression,and vascular clustering signs in the malignant group was higher than that in the benign group(P<0.05);the serum NSE and SCC-Ag levels in the malignant group were higher than those in the benign group Patients(P<0.05).The sensitivity of the combined application of serum NSE,SCC-Ag,and MSCT three-dimensional reconstruction in differential diagnosis of pulmonary benign and malignant nodules was 95.58%,and the specificity was 86.00%.It shows that the combined application of the three-dimensional reconstruction features of MSCT,serum NSE,and SCC-Ag has high sensitivity and specificity in the diagnosis and differentiation of small pulmonary nodules.
作者
侯青
王欣
杨会娟
HOU Qing;WANG Xin;YANG Huijuan(Radiology Department,Beijing Puren Hospital,Beijing 100062,P.R.China;Radiology Department,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,P.R.China;Clinical Laboratory,Beijing Puren Hospital,Beijing 100062,P.R.China)
出处
《影像科学与光化学》
CAS
北大核心
2021年第5期700-704,共5页
Imaging Science and Photochemistry
关键词
多层螺旋CT
三维重建
神经元特异性烯醇化酶
鳞癌相关抗原
肺结节
multi-slice spiral CT
three-dimensional reconstruction
neuron specific enolase
squamous cancinoma-associated antigen
pulmonary nodule
