摘要
目的采用PG-SGA评价卵巢癌患者的营养状况,探讨其在卵巢癌诊治中的临床应用价值。方法选取2020年8月至2021年1月在山西白求恩医院住院的卵巢恶性肿瘤患者为研究对象,共112例,病理结果诊断明确。所有患者入院48 h内,对符合条件的调查对象应用PG-SGA进行营养诊断。PG-SGA评分≥4诊断为存在营养不良,PG-SGA评分≥9诊断为严重营养不良,分析卵巢恶性肿瘤患者营养不良发生的情况,及其与患者的年龄、肿瘤类型、临床病理分期、淋巴结转移、腹水形成、CA125水平等临床病理特征的相关性,以及与其他营养评估指标的一致性。结果所有参与研究的112例卵巢恶性肿瘤患者中,营养不良发生率为75.9%(85/112),重度营养不良发生率为29.4%(33/112)。PG-SGA评分与肿瘤类型、肿瘤临床病理分期、有无腹水、CA125水平有关(P<0.05);PG-SGA评分与BMI、PNI、血红蛋白、上臂围及小腿周径有关(P<0.05)。相较于NSR2002,PG-SGA评价卵巢癌患者营养状况的灵敏度为1.00,特异度为0.403,准确性为64.3%。结论营养不良在卵巢癌患者中发生率高,PG-SGA可以较好地反映卵巢恶性肿瘤患者的营养状况,并与反映病情严重程度的临床病理特征密切相关。
Objective To explore the clinical value of PG-SGA in evaluation of the nutritional status of ovarian cancer patients in the diagnosis and treatment of ovarian cancer.Methods A total of 112 patients with ovarian cancer hospitalized in Shanxi Bethune Hospital from August 2020 to January 2021,with a clear pathological diagnosis,were selected as the research objects.Within 48 h after admission,PG-SGA was applied to all eligible subjects for nutritional diagnosis.PG-SGA score≥4 is diagnosed as malnutrition,and PG-SGA score≥9 is diagnosed as severe malnutrition.The occurrence of malnutrition in patients with ovarian cancer was recorded,its relationship with age,tumor type,clinicopathological stage,lymph node metastasis,ascites formation,CA125 level and other clinicopathological characteristics were analyzed,and the consistency with other nutritional evaluation indicators was evaluated.Results Among the 112 patients with ovarian cancer,the incidence of malnutrition was 75.9%(85/112),and the incidence of severe malnutrition was 29.4%(33/112).PG-SGA was correlated with tumor type,clinicopathological stage,ascites and CA125 level(P<0.05).PG-SGA was significantly correlated with BMI,PNI,hemoglobin,upper arm circumference and leg circumference(P<0.05).Compared with NRS2002,the sensitivity,the specificity and the accuracy of PG-SGA were 1.00,0.403 and 64.3%,respectively.Conclusion Malnutrition has a high incidence rate in ovarian cancer patients.PG-SGA can better reflect the nutritional status of ovarian cancer patients,and it is closely related to the clinicopathological characteristics that reflect the severity of the disease.
作者
郑菲
董南南
王赞宏
ZHENG Fei;DONG Nannan;WANG Zanhong(Department of Obstetrics and Gynecology,Third Hospital of Shanxi Medical University,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Taiyuan 030032,China)
出处
《山西医科大学学报》
CAS
2021年第8期973-977,共5页
Journal of Shanxi Medical University
基金
山西省科技成果转化引导专项二批项目(201604D132043)。
