摘要
目的分析并探究分化型甲状腺癌采取全甲状腺切除术治疗的临床效果及应用安全性。方法研究时间段2018年5月—2019年8月,探究对象为此时间段该院接治的伴分化型甲状腺癌患者,纳入70例,按照双色球法分组,将其分为对照组(n=35)和研究组(n=35),接受次全切术诊疗者纳入对照组,采取全甲状腺切除术诊疗者纳入研究组,比较两组效果,包括有效率、并发症及促甲状腺激素等。结果研究组有效率(97.14%)高于对照组(74.29%),差异有统计学意义(χ^(2)=7.467,P=0.006);与对照组(5.71%)比,研究组低血钙、永久性声音嘶哑等并发症(22.86%)明显升高,差异有统计学意义(χ^(2)=4.200,P=0.400);研究组TSH(0.11±0.07)mIU/L、Tg(0.08±0.03)pmol/L、TgAb(43.59±5.38)μg/L相比于对照组(1.06±0.22)mIU/L、(0.95±1.13)pmol/L、(94.89±11.22)μg/L明显下降,差异有统计学意义(t=24.344、4.553、24.390,P<0.001);研究组术中出血量(54.02±12.17)mL及手术时间(87.75±12.18)min较对照组(83.36±15.57)mL、(105.78±14.12)min显著降低,差异有统计学意义(t=8.783、5.720,P<0.001)。结论分化型甲状腺癌采取全甲状腺切除术治疗效果较为理想,可进行甲状腺相关指标的积极改善,减少术中出血量,但其并发症较多,针对低危亦或是术后无需放疗诊疗患者,建议采取次全切术。
Objective To analyze and explore the clinical effects and application safety of total thyroidectomy for differentiated thyroid cancer.Methods During the study period from May 2018 to Austgust 2019,the subjects of investigation were patients with differentiated thyroid cancer treated in the hospital during this period.70 cases were included and grouped according to the two-color ball method.They were divided into a control group(n=35)and a study group(n=35).Those who received subtotal resection were included in the control group,and those who received total thyroidectomy were included in the study group.The effects of the two groups were compared,including effective rate,complications,and thyroid stimulating hormone.Results The effective rate of the study group(97.14%)was compared with the control group(74.29%),which had a significant improvement advantage,the difference was statistically significant(χ^(2)=7.467,P=0.006);compared with the control group(5.71%),the study group had complications such as hypocalcemia and permanent hoarseness significantly increased(22.86%),the difference was statistically significant(χ^(2)=4.200,P=0.400);TSH(0.11±0.07)mIU/L,Tg(0.08±0.03)pmol/L,TgAb(43.59±5.38)μg/L in the study group compared to the control group(1.06±0.22)mIU/L,(0.95±1.13)pmol/L,(94.89±11.22)μg/L,significantly decreased,the difference was statistically significant(t=24.344,4.553,24.390,P<0.001);intraoperative blood loss(54.02±12.17)mL and operation time(87.75±12.18)min in the study group and the control group(83.36±15.57)mL and(105.78±14.12)min were significantly shortened,the difference was statistically significant(t=8.783,5.720,P<0.001).Conclusion The effect of total thyroidectomy for differentiated thyroid cancer is ideal.It can actively improve thyroid-related indicators and reduce intraoperative blood loss.However,it has many complications.It is aimed at low-risk patients or patients who do not require radiotherapy after surgery.It is recommended to take a subtotal resection.
作者
王勇
WANG Yong(Department of Thyroid and Breast Surgery,Xintai People's Hospital of Shandong Province,Xintai,Shandong Province,271200 China)
出处
《世界复合医学》
2021年第6期39-41,45,共4页
World Journal of Complex Medicine
关键词
分化型甲状腺癌
全甲状腺切除术
并发症
效果
Differentiated thyroid cancer
Total thyroidectomy
Complications
Effect
