摘要
目的探究康柏西普治疗糖尿病视网膜病变合并新生血管性青光眼的疗效。方法该研究资料选取2018年1月—2019年12月该院诊治的60例糖尿病视网膜病变合并新生血管性青光眼患者。经随机数表法予以分组,其中参照组(30例)行全视网膜激光光凝(PRP)治疗,观察组(30例)行康柏西普与全视网膜激光光凝联合治疗。比较两组治疗情况及不良反应发生情况。结果观察组治疗后1周、治疗后1、3、6个月时房角新生血管完全消退占比及虹膜新生血管完全消退占比高于参照组,差异有统计学意义(P<0.05)。观察组治疗后1周,治疗后1、3、6个月时眼压均低于参照组,差异有统计学意义(P<0.05)。观察组治疗后1周,治疗后1、3、6个月时BCVA均高于参照组,差异有统计学意义(P<0.05)。两组治疗前视网膜厚度、黄斑中心凹厚度相比,差异无统计学意义(P>0.05)。两组治疗后视网膜厚度低于治疗前,且观察组低于参照组;黄斑中心凹厚度高于治疗前,且观察组高于参照组,差异有统计学意义(P<0.05)。观察组不良反应发生率低于参照组,差异有统计学意义(P<0.05)。结论予以糖尿病视网膜病变合并新生血管性青光眼患者全视网膜激光光凝治疗基础上的康博西普治疗效果确切,利于患者眼压降低、视力提高,且较为安全,可行推广。
Objective To explore the efficacy of Conbercept in the treatment of diabetic retinopathy with neovascular glaucoma.Methods The selected time period for this study was from January 2018 to December 2019.The patients were 60 diabetic retinopathy patients with neovascular glaucoma who were diagnosed and treated in the hospital.They were divided into groups by random number table.The reference group(30 cases)were treated with panretinal laser photocoagulation(PRP),and the observation group(30 cases)was treated with conbercept and panretinal laser photocoagulation.The treatment and the occurrence of adverse reactions between the two groups were compared.Results The ratio of complete regression of angle neovascularization and complete regression of iris neovascularization in the observation group 1 week after treatment,1,3,and 6 months after treatment was higher than that of the reference group,and the difference was statistically significant(P<0.05).The intraocular pressure of the observation group was lower than that of the reference group 1 week after treatment,1,3,and 6 months after treatment,and the difference was statistically significant(P<0.05).The BCVA of the observation group was higher than that of the reference group 1 week after treatment,1,3,and 6 months after treatment,and the difference was statistically significant(P<0.05).The thickness of the retina and the thickness of the fovea were compared between the two groups before treatment,and the difference was not statistically significant(P>0.05).The thickness of the retina after treatment in the two groups was lower than before treatment,and the observation group was lower than the reference group;the fovea thickness was higher than before treatment,and the observation group was higher than the reference group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the reference group,and the difference was statistically significant(P<0.05).Conclusion The therapeutic effe
作者
王勇
WANG Yong(Department of Ophthalmology,Yishui County People's Hospital,Linyi,Shandong Province,276400 China)
出处
《糖尿病新世界》
2021年第11期162-165,共4页
Diabetes New World Magazine
