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骨质疏松性腰椎椎体压缩性骨折的危险因素分析 被引量:17

Analysis of Risk Factors for Osteoporotic LumbarVertebral Compression Fracture
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摘要 目的:探讨分析骨质疏松性腰椎椎体压缩性骨折发生的危险因素。方法:回顾性分析2013年9月至2020年9月在本院确诊收治的691例骨质疏松症患者的临床资料。收集患者性别、年龄、病程、骨密度T值、体质量指数(BMI)、2型糖尿病史、高血压病史、吸烟史、饮酒史、维生素D及钙剂服用史以及运动锻炼史等临床资料,并对上述可能与骨质疏松性腰椎椎体压缩性骨折相关的影响因素进行单因素分析以及多因素Logistic回归分析。结果:单因素分析结果显示,骨质疏松性腰椎椎体压缩性骨折的发生与性别、年龄、骨密度T值、BMI、2型糖尿病史、吸烟史、饮酒史、维生素D及钙剂服用史以及运动锻炼史的关系密切(P<0.05)。多因素Logistic回归分析结果显示,女性(P=0.015)、高龄(P<0.001)、较低骨密度T值(P<0.001)、较高BMI(P<0.001)、2型糖尿病史(P<0.001)、吸烟史(P=0.017)和饮酒史(P=0.001)均为骨质疏松性腰椎椎体压缩性骨折的危险因素。结论:女性、高龄、较低骨密度T值、较高BMI、2型糖尿病史、吸烟史、饮酒史均为骨质疏松性腰椎椎体压缩性骨折的危险因素,临床工作者需高度关注上述危险因素。 Objective:To investigate the risk factors of osteoporotic vertebral compression fracture of the lumbar vertebra.Methods:The clinical data of 691 patients with osteoporosis admitted and treated in hospital from September 2013 to September 2020 were retrospectively analyzed.Patients’gender,age,course,bone mineral density Tvalue,body mass index(BMI),history of type 2 diabetes mellitus,history of hypertension,smoking history,drinking history and history during taking vitamin D and calcium supplements,and the history of exercise were collected.Univariate analysis and multivariate logistic regression analysis were performed on the above influencing factors that may be related to osteoporotic lumbar vertebral compression fracture.Results:Univariate analysis results showed that the occurrence of osteoporotic lumbar vertebral compression fractures was closely related to gender,age,bone mineral density Tvalue,BMI,history of type 2 diabetes mellitus,smoking history,drinking history and history during taking vitamin D and calcium supplements,and the history of exercise(P<0.05).Multivariate logistic regression analysis results show that the female(P=0.015),age(P<0.001),lower bone density Tvalue(P< 0.001),higher BMI(P<0.001),history of type 2 diabetes mellitus(P<0.001),smoking history(P=0.017)and drinking history(P=0.001)are the osteoporotic risk factors of lumbar vertebral compression fractures.Conclusion:This study shows that female,older age,lower bone density Tvalue,higher BMI,history of type 2 diabetes mellitus,smoking history,drinking history are osteoporotic risk factors of lumbar vertebral compression fractures.Clinical practitioners should pay close attention to the above risk factors.
作者 王杰 杨宝辉 李浩鹏 WANG Jie;YANG Baohui;LI Haopeng(Department of Spinal Surgery,The Second Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710004,China)
出处 《中国中医骨伤科杂志》 CAS 2021年第8期29-33,共5页 Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金 中央高校基本科研业务费专项基金(ZRZD2017008) 白求恩脊柱病理性骨折椎体强化治疗专项基金(BK-JP2017003)。
关键词 骨质疏松症 腰椎椎体压缩性骨折 危险因素 回顾性研究 单因素分析 回归分析 osteoporosis compression fracture of the lumbar vertebra risk factors retrospective study univariate analysis logistic regression analysis
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